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学科主题基础医学
HMDD v2.0: a database for experimentally supported human microRNA and disease associations
Li, Yang1,2; Qiu, Chengxiang3; Tu, Jian2,4; Geng, Bin4; Yang, Jichun4; Jiang, Tianzi3; Cui, Qinghua2,4
刊名NUCLEIC ACIDS RESEARCH
2014
DOI10.1093/nar/gkt1023
42期:D1页:D1070-D1074
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology
研究领域[WOS]Biochemistry & Molecular Biology
关键词[WOS]HUMAN CANCERS ; SIMILARITY ; BIOGENESIS ; GENES
英文摘要

The Human microRNA Disease Database (HMDD; available via the Web site at http://cmbi.bjmu.edu.cn/hmdd and http://202.38.126.151/hmdd/tools/hmdd2.html) is a collection of experimentally supported human microRNA (miRNA) and disease associations. Here, we describe the HMDD v2.0 update that presented several novel options for users to facilitate exploration of the data in the database. In the updated database, miRNA-disease association data were annotated in more details. For example, miRNA-disease association data from genetics, epigenetics, circulating miRNAs and miRNA-target interactions were integrated into the database. In addition, HMDD v2.0 presented more data that were generated based on concepts derived from the miRNA-disease association data, including disease spectrum width of miRNAs and miRNA spectrum width of human diseases. Moreover, we provided users a link to download all the data in the HMDD v2.0 and a link to submit novel data into the database. Meanwhile, we also maintained the old version of HMDD. By keeping data sets up-to-date, HMDD should continue to serve as a valuable resource for investigating the roles of miRNAs in human disease.

语种英语
WOS记录号WOS:000331139800157
项目编号2012CB517506 ; 2012CB517806 ; 31000653 ; 31000651
资助机构National Basic Research program of China ; National Natural Science Foundation of China ; NSFC
引用统计
被引频次:187[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/57530
专题北京大学基础医学院_细胞生物学系
北京大学基础医学院
作者单位1.Peking Univ, Sch Basic Med Sci, Dept Cell Biol, Beijing 100191, Peoples R China
2.Peking Univ, Sch Basic Med Sci, Dept Biomed Informat, Beijing 100191, Peoples R China
3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China
4.Peking Univ, MOE Key Lab Cardiovasc Sci, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Li, Yang,Qiu, Chengxiang,Tu, Jian,et al. HMDD v2.0: a database for experimentally supported human microRNA and disease associations[J]. NUCLEIC ACIDS RESEARCH,2014,42(D1):D1070-D1074.
APA Li, Yang.,Qiu, Chengxiang.,Tu, Jian.,Geng, Bin.,Yang, Jichun.,...&Cui, Qinghua.(2014).HMDD v2.0: a database for experimentally supported human microRNA and disease associations.NUCLEIC ACIDS RESEARCH,42(D1),D1070-D1074.
MLA Li, Yang,et al."HMDD v2.0: a database for experimentally supported human microRNA and disease associations".NUCLEIC ACIDS RESEARCH 42.D1(2014):D1070-D1074.
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