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学科主题: 基础医学
题名:
HMDD v2.0: a database for experimentally supported human microRNA and disease associations
作者: Li, Yang1,2; Qiu, Chengxiang3; Tu, Jian2,4; Geng, Bin4; Yang, Jichun4; Jiang, Tianzi3; Cui, Qinghua2,4
刊名: NUCLEIC ACIDS RESEARCH
发表日期: 2014
DOI: 10.1093/nar/gkt1023
卷: 42, 期:D1, 页:D1070-D1074
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemistry & Molecular Biology
研究领域[WOS]: Biochemistry & Molecular Biology
关键词[WOS]: HUMAN CANCERS ; SIMILARITY ; BIOGENESIS ; GENES
英文摘要:

The Human microRNA Disease Database (HMDD; available via the Web site at http://cmbi.bjmu.edu.cn/hmdd and http://202.38.126.151/hmdd/tools/hmdd2.html) is a collection of experimentally supported human microRNA (miRNA) and disease associations. Here, we describe the HMDD v2.0 update that presented several novel options for users to facilitate exploration of the data in the database. In the updated database, miRNA-disease association data were annotated in more details. For example, miRNA-disease association data from genetics, epigenetics, circulating miRNAs and miRNA-target interactions were integrated into the database. In addition, HMDD v2.0 presented more data that were generated based on concepts derived from the miRNA-disease association data, including disease spectrum width of miRNAs and miRNA spectrum width of human diseases. Moreover, we provided users a link to download all the data in the HMDD v2.0 and a link to submit novel data into the database. Meanwhile, we also maintained the old version of HMDD. By keeping data sets up-to-date, HMDD should continue to serve as a valuable resource for investigating the roles of miRNAs in human disease.

语种: 英语
所属项目编号: 2012CB517506 ; 2012CB517806 ; 31000653 ; 31000651
项目资助者: National Basic Research program of China ; National Natural Science Foundation of China ; NSFC
WOS记录号: WOS:000331139800157
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57530
Appears in Collections:基础医学院_细胞生物学系_期刊论文

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作者单位: 1.Peking Univ, Sch Basic Med Sci, Dept Cell Biol, Beijing 100191, Peoples R China
2.Peking Univ, Sch Basic Med Sci, Dept Biomed Informat, Beijing 100191, Peoples R China
3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China
4.Peking Univ, MOE Key Lab Cardiovasc Sci, Beijing 100191, Peoples R China

Recommended Citation:
Li, Yang,Qiu, Chengxiang,Tu, Jian,et al. HMDD v2.0: a database for experimentally supported human microRNA and disease associations[J]. NUCLEIC ACIDS RESEARCH,2014,42(D1):D1070-D1074.
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