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Morphology of bacterial flora in root canals associated with apical abscesses
Guo Huijie1; Gao Chengzhi1; Zhang Chengfei3; Zheng Shuying2; Yue Lin4
关键词Apical Abscess Biofilm Clinical Symptoms Dentinal Tubules Endodontic Infection
刊名CHINESE MEDICAL JOURNAL
2014-09-20
DOI10.3760/cma.j.issn.0366-6999.20140965
127期:18页:3254-3258
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
研究领域[WOS]General & Internal Medicine
关键词[WOS]DENTINAL TUBULES ; ENDODONTIC INFECTIONS ; PERIODONTITIS ; TEETH ; BIOFILMS
英文摘要

Background Apical abscess is an inflammatory process in the peri-radicular tissues caused by biofilms in the necrotic root canal systems. Therefore, a comprehensive analysis of the bacterial colonization is required for a better understanding of the pathogenesis. This study aimed to investigate the patterns of bacterial infection of root canals of teeth with apical abscesses and to determine whether histological and microbiological findings correlated with clinical conditions.

Methods Eighteen samples from 18 teeth with apical pathological lesions were analyzed. Nine patients with acute apical abscesses experienced severe pain, and nine patients were asymptomatic with a sinus tract. After extraction, each affected root was divided into two halves. One half was processed for histobacteriologic analysis and examined using light microscopy, and the other half was analyzed using scanning electron microscopy (SEM) to determine the patterns of microbial colonization of the root canals.

Results The appearance of each sample subjected to SEM was consistent with the histobacteriologic findings despite the presence or absence of clinical symptoms. Intraradicular biofilms comprising cocci, rods, and/or filaments of amorphous materials were observed in the apical third of the main root canals in all samples. The bacterial biofilms covering the main root canal walls also penetrated the dentinal tubules to varying depths. The morphologies of biofilms varied, and a unique pattern of intraradicular infection was not identified.

Conclusion Intraradicular infections formed complex and variable multispecies biofilms and their presence did not correlate with clinical symptoms.

语种英语
WOS记录号WOS:000343337300012
项目编号8107088
资助机构National Natural Science Foundation of China
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/57578
专题北京大学第二临床医学院_口腔科
北京大学口腔医学院_牙体牙髓科
作者单位1.Peking Univ, Peoples Hosp, Dept Stomatol, Beijing 100044, Peoples R China
2.Peking Univ, Peoples Hosp, Electron Microscopy Lab, Beijing 100044, Peoples R China
3.Univ Hong Kong, Fac Dent, Hong Kong, Hong Kong, Peoples R China
4.Peking Univ, Sch & Hosp Stomatol, Dept Cariol Endodontol & Operat Dent, Beijing 100081, Peoples R China
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GB/T 7714
Guo Huijie,Gao Chengzhi,Zhang Chengfei,et al. Morphology of bacterial flora in root canals associated with apical abscesses[J]. CHINESE MEDICAL JOURNAL,2014,127(18):3254-3258.
APA Guo Huijie,Gao Chengzhi,Zhang Chengfei,Zheng Shuying,&Yue Lin.(2014).Morphology of bacterial flora in root canals associated with apical abscesses.CHINESE MEDICAL JOURNAL,127(18),3254-3258.
MLA Guo Huijie,et al."Morphology of bacterial flora in root canals associated with apical abscesses".CHINESE MEDICAL JOURNAL 127.18(2014):3254-3258.
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