北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学口腔医学院  > 牙周科  > 期刊论文
学科主题: 口腔医学
题名:
Association of Carotid Intima-media Thickness and Atherosclerotic Plaque with Periodontal Status
作者: Yu, H.1; Qi, L. T.2; Liu, L. S.3; Wang, X. Y.3; Zhang, Y.1; Huo, Y.2; Luan, Q. X.1
关键词: atherosclerosis ; periodontitis ; periodontal attachment loss ; oral hygiene ; hyperglycemia ; cardiovascular diseases
刊名: JOURNAL OF DENTAL RESEARCH
发表日期: 2014-08-01
DOI: 10.1177/0022034514538973
卷: 93, 期:8, 页:744-751
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Dentistry, Oral Surgery & Medicine
研究领域[WOS]: Dentistry, Oral Surgery & Medicine
关键词[WOS]: WALL THICKNESS ; INFLAMMATION ; DISEASE ; RISK ; JAPAN
英文摘要:

Studies have suggested an association between clinical/subclinical atherosclerosis and periodontal status. The purpose of this study was to investigate the association among maximal carotid intima-media thickness (cIMT), atherosclerotic plaque, and periodontal status in Chinese elderly patients. A crosssectional study was conducted of 847 participants (age, 70.64 +/- 9.03 yr) with = 10 teeth. A questionnaire survey, routine biochemical tests, a periodontal examination, and maximal cIMT measurement were performed for each. Traditional risk factors for atherogenesis were considered in the statistical analysis. Mean plaque index, which reflects oral hygiene, was correlated with maximal cIMT and atherosclerotic plaque in the study sample overall (beta = 0.068, p < .001; OR = 2.051, p < .001) and in euglycemic participants (beta = 0.066, p = .008; odds ratio = 2.122, p = .009). In hyperglycemic participants, multiple linear regression analysis (p = .006) and multivariate logistic regression analysis (p = .025) revealed a linear and dose-dependent association between mean clinical attachment loss and maximal cIMT after adjustment for traditional risk factors. Each 1-mm increase in mean clinical attachment loss corresponded to a 0.018-mm increase in maximal cIMT. The risk of atherosclerotic plaque increased by 18.3% with each 1-mm increase in mean clinical attachment loss. Other indicators of periodontal exposure, including percentage of sites with attachment loss = 3 to 5 mm (3%-5%), were also correlated with cIMT and atherosclerotic plaque in hyperglycemic patients. In this elderly population, a linear and dose-dependent association among mean clinical attachment loss, attachment loss 3% to 5%, maximal cIMT, and atherosclerotic plaque was verified in those with hyperglycemia. Poor oral hygiene was correlated with maximal cIMT and atherosclerotic plaque in all participants, including those with normal blood glucose.

语种: 英语
项目资助者: Capital Medical Development Funds, China
WOS记录号: WOS:000339325200004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57586
Appears in Collections:北京大学口腔医学院_牙周科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Sch & Hosp Stomatol, Dept Periodontol, Beijing 100871, Peoples R China
2.Peking Univ, Hosp 1, Dept Cardiol, Beijing 100871, Peoples R China
3.Beijing Hypertens League Inst, Lab Human Genet, Beijing, Peoples R China

Recommended Citation:
Yu, H.,Qi, L. T.,Liu, L. S.,et al. Association of Carotid Intima-media Thickness and Atherosclerotic Plaque with Periodontal Status[J]. JOURNAL OF DENTAL RESEARCH,2014,93(8):744-751.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Yu, H.]'s Articles
[Qi, L. T.]'s Articles
[Liu, L. S.]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Yu, H.]‘s Articles
[Qi, L. T.]‘s Articles
[Liu, L. S.]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace