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A clinicopathologic study on basaloid squamous cell carcinoma in the oral and maxillofacial region
Yu, G. -Y.1,2; Gao, Y.3,4; Peng, X.1,2; Chen, Y.3,4; Zhao, F. -Y.1,2; Wu, M-J1,2
关键词Basaloid Squamous Cell Carcinoma Squamous Cell Carcinoma Oral Mucosa Head And Neck Diagnosis Prognosis Pathology Immunohistochemistry
刊名INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
2008-11-01
DOI10.1016/j.ijom.2008.05.019
37期:11页:1003-1008
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Dentistry, Oral Surgery & Medicine ; Surgery
研究领域[WOS]Dentistry, Oral Surgery & Medicine ; Surgery
关键词[WOS]ADENOID CYSTIC CARCINOMA ; DIFFERENTIAL-DIAGNOSIS ; LARYNX ; HYPOPHARYNX ; NECK ; HEAD ; NEOPLASM ; FEATURES ; CAVITY ; TRACT
英文摘要

Basaloid squamous Cell carcinoma (BSCC) is a rare distinct variant of squamous Cell carcinoma (SCC). To investigate its clinical behavior and prognosis, 15 patients with BSCC in the oral and maxillofacial region were clinically analyzed and compared with 15 patients with conventional SCC matched for site, stage, gender and age. TO understand its immunohistochemical features, sections for cytokeratin AE1/AE3, CK 13. CK 7, CK 8, proliferating cell nuclear antigen (PCNA) and p53 were reviewed from 12 patients with BSCC. The rate of cervical lymph node metastasis of BSCC was as high as 67% and that of distant metastasis 13%. The tumor recurrence rate was 33% and the 3-year and 5-year Survival rates were 53% and 32%, respectively. For conventional SCC, the cervical lymph node metastasis rate was 27%, that of distant metastasis 7%, tumor recurrence rate was 33%, and 3-year and 5-year survival rates were 80% and 70%, respectively. In most BSCC patients(10/12)the PCNA index was over 50%. Twelve BSCC patients were diagnosed with grade II or III conventional SCC when the original records of the primary diagnosis for the 15 patients with BSCC were reviewed. The biological behavior and prognosis of BSCC are similar to those of poorly differentiated SCC.

语种英语
WOS记录号WOS:000261328000005
引用统计
被引频次:20[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/57601
专题北京大学口腔医学院
北京大学口腔医学院_外科
作者单位1.Peking Univ, Dept Oral & Maxillofacial Surg, Sch Stomatol, Beijing 100081, Peoples R China
2.Peking Univ, Dept Oral & Maxillofacial Surg, Hosp Stomatol, Beijing 100081, Peoples R China
3.Peking Univ, Dept Oral Pathol, Sch Stomatol, Beijing 100081, Peoples R China
4.Peking Univ, Dept Oral Pathol, Hosp Stomatol, Beijing 100081, Peoples R China
推荐引用方式
GB/T 7714
Yu, G. -Y.,Gao, Y.,Peng, X.,et al. A clinicopathologic study on basaloid squamous cell carcinoma in the oral and maxillofacial region[J]. INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY,2008,37(11):1003-1008.
APA Yu, G. -Y.,Gao, Y.,Peng, X.,Chen, Y.,Zhao, F. -Y.,&Wu, M-J.(2008).A clinicopathologic study on basaloid squamous cell carcinoma in the oral and maxillofacial region.INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY,37(11),1003-1008.
MLA Yu, G. -Y.,et al."A clinicopathologic study on basaloid squamous cell carcinoma in the oral and maxillofacial region".INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY 37.11(2008):1003-1008.
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