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学科主题: 口腔医学
题名:
Three-dimensional verification of I-125 seed stability after permanent implantation in the parotid gland and periparotid region
作者: Fan, Yi1; Huang, Ming-Wei1; Zheng, Lei1; Zhao, Yi-Jiao2,3; Zhang, Jian-Guo1
关键词: I-125 seed implantation ; Stability ; Parotid gland ; 3D reconstruction
刊名: RADIATION ONCOLOGY
发表日期: 2015-11-24
DOI: 10.1186/s13014-015-0552-z
卷: 10
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Oncology ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: INTERSTITIAL PROSTATE BRACHYTHERAPY ; RECURRENT ; CANCER ; MIGRATION ; EMBOLIZATION ; TUMORS ; LUNG ; HEAD
英文摘要:

Objective: To evaluate seed stability after permanent implantation in the parotid gland and periparotid region via a three-dimensional reconstruction of CT data.

Material and methods: Fifteen patients treated from June 2008 to June 2012 at Peking University School and Hospital of Stomatology for parotid gland tumors with postoperative adjunctive I-125 interstitial brachytherapy were retrospectively reviewed in this study. Serial CT data were obtained during follow-up. Mimics and Geomagic Studio software were used for seed reconstruction and stability analysis, respectively.

Results: Seed loss and/or migration outside of the treated area were absent in all patients during follow-up (23-71 months). Total seed cluster volume was maximized on day 1 post-implantation due to edema and decreased significantly by an average of 13.5 % (SD = 9.80 %; 95 % CI, 6.82-17.68 %) during the first two months and an average of 4.5 % (SD = 3.60 %; 95 % CI, 2.29-6.29 %) during the next four months. Volume stabilized over the subsequent six months.

Conclusions: I-125 seed number and location were stable with a general volumetric shrinkage tendency in the parotid gland and periparotid region. Three-dimensional seed reconstruction of CT images is feasible for visualization and verification of implanted seeds in parotid brachytherapy.

语种: 英语
WOS记录号: WOS:000365257400004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57605
Appears in Collections:北京大学口腔医学院_期刊论文

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作者单位: 1.Natl Engn Lab Digital & Mat Technol Stomatol, Beijing, Peoples R China
2.Peking Univ, Sch & Hosp Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100871, Peoples R China
3.Peking Univ, Sch & Hosp Stomatol, Ctr Digital Dent, Beijing 100871, Peoples R China

Recommended Citation:
Fan, Yi,Huang, Ming-Wei,Zheng, Lei,et al. Three-dimensional verification of I-125 seed stability after permanent implantation in the parotid gland and periparotid region[J]. RADIATION ONCOLOGY,2015,10.
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