|Clinical characteristics of polypoidal choroidal vasculopathy in Chinese patients|
|Hou, Jing1,2; Tao, Yong1,2; Li, Xiao-xin1,2; Zhao, Ming-wei1,2|
|关键词||Polypoidal Choroidal Vasculopathy Exudative Age-related Macular Degeneration Choroidal Neovascularization Chinese|
|刊名||GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY|
|WOS标题词||Science & Technology|
|关键词[WOS]||INDOCYANINE GREEN VIDEOANGIOGRAPHY ; MACULAR DEGENERATION ; JAPANESE PATIENTS|
To describe the clinical characteristics of polypoidal choroidal vasculopathy (PCV) in a large number of Chinese patients.
This study enrolled 204 consecutive patients (246 eyes) in our department who were diagnosed as having polypoidal choroidal vasculopathy PCV. Patients underwent ophthalmologic examinations including best-corrected visual acuity (BCVA) testing, ophthalmoscopy, fundus photography, fluorescein angiography, indocyanine green angiography, and optic coherence tomography.
Mean patient age was 66.1 years and 60.3% were men. Of the cases, 79.4% were unilateral and 51.2% of BCVA was less than 35 letters. In 171 eyes (69.5%), polypoidal lesions were located in the macula area. Among them, polypoidal lesions were located in the foveal area in 29 eyes (11.8%), in the parafoveal area in 50 eyes (20.3%), and in the extrafoveal area in 88 eyes (35.8%), in both the foveal and parafoveal area in three eyes (1.2%), and in both the parafoveal and extrafoveal area in one eye (0.4%). In 37 eyes (15.0%), PCV lesions were under the temporal retinal vascular arcade; in 11 eyes (4.5%), PCV lesions were found peripapillary. PCV lesion formation was single in 88 eyes (35.8%), cluster in 145 eyes (59.0%), string in two eyes (0.8%), and branch in two eyes (0.8%). In nine eyes (3.6%), the formation of PCV lesions showed both single and cluster shape in the same eye. There were 54.5% with drusen, 44.7% with serous PED, 20.7% with hemorrhagic PED, and 39.0% with neuroretinal detachment.
The majority of Chinese PCV patients were male, unilateral, and showed macular polyps. Drusen, serous PED, hemorrhagic PED, and neuroretinal detachment on OCT were commonly seen.
|项目编号||2005CB724307 ; 30901639 ; 2009B04 ; B2009B041|
|资助机构||Major State Basic Research Development Program of China ; National Natural Science Foundation of China ; Beijing Novel Program ; Special Funds for Central Health research projects, China ; Epidemiological Survey and Consultation Network Construction of Polypoidal Choroidal Vasculopathy in the Beijing Region|
|作者单位||1.Minist Educ, Key Lab Vis Loss & Restorat, Beijing, Peoples R China|
2.Peking Univ, Dept Ophthalmol, Peoples Hosp, Beijing 100044, Peoples R China
|Hou, Jing,Tao, Yong,Li, Xiao-xin,et al. Clinical characteristics of polypoidal choroidal vasculopathy in Chinese patients[J]. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY,2011,249(7):975-979.|
|APA||Hou, Jing,Tao, Yong,Li, Xiao-xin,&Zhao, Ming-wei.(2011).Clinical characteristics of polypoidal choroidal vasculopathy in Chinese patients.GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY,249(7),975-979.|
|MLA||Hou, Jing,et al."Clinical characteristics of polypoidal choroidal vasculopathy in Chinese patients".GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 249.7(2011):975-979.|