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学科主题: 公共卫生
题名:
Association between Ambient Temperature and Blood Pressure and Blood Pressure Regulators: 1831 Hypertensive Patients Followed Up for Three Years
作者: Chen, Qing1,2; Wang, Jinwei2; Tian, Jun2; Tang, Xun2; Yu, Canqing2; Marshall, Roger J.3; Chen, Dafang2; Cao, Weihua2; Zhan, Siyan2; Lv, Jun2; Lee, Liming2; Hu, Yonghua2
刊名: PLOS ONE
发表日期: 2013-12-31
DOI: 10.1371/journal.pone.0084522
卷: 8, 期:12
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Multidisciplinary Sciences
研究领域[WOS]: Science & Technology - Other Topics
关键词[WOS]: CONVERTING ENZYME-INHIBITOR ; FLOW-MEDIATED DILATION ; OUTDOOR TEMPERATURE ; CAROTID ATHEROSCLEROSIS ; ALCOHOL-CONSUMPTION ; BRACHIAL-ARTERY ; VARIABILITY ; COLD ; POPULATION ; MORTALITY
英文摘要:

Several studies have suggested an association between ambient air temperature and blood pressure. However, this has not been reliably confirmed by longitudinal studies. Also, whether the reaction to temperature stimulation is modified by other factors such as antihypertensive medication is rarely investigated. The present study explores the relationship between ambient temperature and blood pressure, without and with antihypertensive medication, in a study of 1,831 hypertensive patients followed up for three years, in two or four weekly check ups, accumulating 62,452 follow-up records. Both baseline and follow-up blood pressure showed an inverse association with ambient temperature, which explained 32.4% and 65.6% of variation of systolic blood pressure and diastolic blood pressure (P < 0.05) respectively. The amplitude of individual blood pressure fluctuation with temperature throughout a year (a 29 degrees centigrade range) was 9.4/7.3 mmHg. Medication with angiotensin converting enzyme inhibitor benazepril attenuated the blood pressure fluctuation by 2.4/1.3 mmHg each year, though the inverse association of temperature and blood pressure remained. Gender, drinking behavior and body mass index were also found to modify the association between temperature and diastolic blood pressure. The results indicate that ambient temperature may negatively regulate blood pressure. Hypertensive patients should monitor and treat blood pressure more carefully in cold days, and it could be especially important for the males, thinner people and drinkers.

语种: 英语
所属项目编号: 96-906-02-05 ; 2001BAF03B02 ; 2006BAI01A03- ( 16)
项目资助者: National Key Technologies R&amp ; D Program of China for the 9th Five-Year Plan ; National Key Technologies R&amp ; D Program of China for the 10th Five-Year Plan ; Mega-projects of Science Research for the 11th Five-Year Plan
WOS记录号: WOS:000329323900105
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57631
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: 1.Third Mil Med Univ, Coll Prevent Med, Dept Hygien Toxicol, Chongqing, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing 100871, Peoples R China
3.Univ Auckland, Sch Populat Hlth, Sect Epidemiol & Biostat, Auckland 1, New Zealand

Recommended Citation:
Chen, Qing,Wang, Jinwei,Tian, Jun,et al. Association between Ambient Temperature and Blood Pressure and Blood Pressure Regulators: 1831 Hypertensive Patients Followed Up for Three Years[J]. PLOS ONE,2013,8(12).
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