IR@PKUHSC  > 北京大学第二临床医学院  > 心血管内科
学科主题临床医学
Real world clinical performance of the zotarolimus eluting coronary stent system in Chinese patients: a prospective, multicenter registry study
Han Ya-ling1; Chen Ji-yan2; Xu Bo3; Yan Hong-bing4; Wang Le-feng6; Li Wei-min7; Cong Hong-liang8; Jing Quan-min1; Wang Shou-li1; Xu Kai1; Wang Wei-min9; Huo Yong10
关键词Drug Eluting Stents Asian Continental Ancestry Group Registries
刊名CHINESE MEDICAL JOURNAL
2011-10-20
DOI10.3760/cma.j.issn.0366-6999.2011.20.009
124期:20页:3255-3259
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
研究领域[WOS]General & Internal Medicine
关键词[WOS]ENDEAVOR-II TRIAL ; BARE-METAL STENTS ; UNSELECTED POPULATION ; REWARDS REGISTRY ; ARTERY-DISEASE ; THROMBOSIS ; OUTCOMES ; LESIONS ; SAFETY ; IMPLANTATION
英文摘要

Background Early clinical trials with the Endeavor zotarolimus eluting stent (ZES) in western populations demonstrated low rates of target lesion revascularization with a favorable safety profile including low late stent thrombosis with up to 5 years of follow-up. The aim of this clinical registry study was to evaluate real world clinical performance of the ZES coronary system in Chinese patients.

Methods The China Endeavor Registry is a prospective, multicenter registry assessing the safety of the ZES system in a real world patient population. It was conducted at 46 centers in China in routine treatment of patients with coronary artery stenosis, including patients with clinical characteristics or lesion types that are often excluded from randomized controlled trials. The registry included 2210 adult patients who underwent single-vessel or multi-vessel percutaneous coronary intervention. The primary end point was the rate of major adverse cardiac events (MACE) at 12 months.

Results The 12-month rate of MACE for all patients in the registry was 3.03%. Cardiac death or myocardial infarction rate was 1.28% and target lesion revascularization rate was 1.66%, non-target lesion target vessel revascularization (TVR) was 0.52%, TVR was 2.18%, and target vessel failure was 3.22%. There was only one case of emergent cardiac bypass surgery. The 12-month overall incidence of all Academic Research Consortium (ARC)-defined stent thrombosis was 0.43%.

Conclusion Mid-term results from the real-world China Endeavor Registry suggest that Endeavor ZES was safe and effective in Chinese patients. Chin Med J 2011;124(20):3255-3259

语种英语
WOS记录号WOS:000296307700009
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被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/57668
专题北京大学第二临床医学院_心血管内科
作者单位1.Shenyang No Hosp, Inst Cardiovasc Res Peoples Liberat Army, Dept Cardiol, Shenyang 110840, Liaoning, Peoples R China
2.Guangdong Acad Med Sci, Guangdong Gen Hosp, Dept Cardiol, Guangzhou 510080, Guangdong, Peoples R China
3.Peking Union Med Coll, Fuwai Hosp, Cardiac Catheterizat Lab, Beijing 100037, Peoples R China
4.Peking Union Med Coll, Fuwai Hosp, Dept Cardiol, Beijing 100037, Peoples R China
5.Chinese Acad Med Sci, Beijing 100037, Peoples R China
6.Capital Med Univ, Ctr Heart, Beijing Chao Yang Hosp, Beijing 100020, Peoples R China
7.Tianjin Chest Hosp, Dept Cardiol, Tianjin 300051, Peoples R China
8.Harbin Med Coll, Dept Cardiol, Affiliated Hosp 1, Harbin 150001, Peoples R China
9.Peking Univ, Peoples Hosp, Dept Cardiol, Beijing 100044, Peoples R China
10.Peking Univ, Hosp 1, Dept Cardiol, Beijing 100034, Peoples R China
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Han Ya-ling,Chen Ji-yan,Xu Bo,et al. Real world clinical performance of the zotarolimus eluting coronary stent system in Chinese patients: a prospective, multicenter registry study[J]. CHINESE MEDICAL JOURNAL,2011,124(20):3255-3259.
APA Han Ya-ling.,Chen Ji-yan.,Xu Bo.,Yan Hong-bing.,Wang Le-feng.,...&Huo Yong.(2011).Real world clinical performance of the zotarolimus eluting coronary stent system in Chinese patients: a prospective, multicenter registry study.CHINESE MEDICAL JOURNAL,124(20),3255-3259.
MLA Han Ya-ling,et al."Real world clinical performance of the zotarolimus eluting coronary stent system in Chinese patients: a prospective, multicenter registry study".CHINESE MEDICAL JOURNAL 124.20(2011):3255-3259.
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