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学科主题: 临床医学
题名:
Reduction of atrial fibrillation in remotely monitored pacemaker patients: results from a Chinese multicentre registry
作者: Chen Ke-ping1,2,3; Dai Yan1,2,3; Hua Wei1,2,3; Yang Jie-fu4; Li Kang5; Liang Zhao-guang6; Shen Fa-rong7; Chen Si-lin8; Su Yan-gang9; Ding Yan-sheng10; Zhang Shu1,2,3
关键词: home monitoring ; atrial fibrillation burden ; pacemaker ; cardiac resynchronization device
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2013-11-20
DOI: 10.3760/cma.j.issn.0366-6999.20130106
卷: 126, 期:22, 页:4216-4221
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: IMPLANTABLE-CARDIOVERTER-DEFIBRILLATORS ; CARDIAC RESYNCHRONIZATION THERAPY ; UP TRUST TRIAL ; FOLLOW-UP ; HEART-FAILURE ; MANAGEMENT ; DIAGNOSTICS ; EFFICACY ; IMPACT ; PERFORMANCE
英文摘要:

Background Many recipients of implantable cardiac electronic devices have atrial fibrillation (AF) occurrences after device implantation, even if there is no previous history of AF, and some of the episodes are asymptomatic. The purpose of this study was to evaluate trends in AF burden following early AF detection in patients treated with pacemakers equipped with automatic, daily Home Monitoring function.

Methods Between February 2009 and December 2010, the registry recruited 701 pacemaker patients (628 dual-chamber, 73 biventricular devices) at 97 clinical centers in China. Daily Home Monitoring data transmissions were analyzed to screen for the AF burden. In-office follow-ups were scheduled for 3 and 6 months after implantation. Upon first AF (i.e., mode-switch) detection in a patient, screening of AF burden by Home Monitoring was extended for the next 180 days.

Results At least one episode of AF was observed in 22.9% of patients with dual-chamber pacemakers and in 28.8% of patients with biventricular pacemakers. The first AF detection in a patient occurred, on average, about 2 months before scheduled follow-up visits. In both pacemaker groups, mean AF burden decreased significantly (P<0.05) over 180 days following first AF detection: from 12.0% to 2.5% in dual-chamber and from 12.2% to 0.5% in biventricular pacemaker recipients. The number of patients with an AF burden >10% per month was significantly reduced over 6 months of implantation in both dual chamber (38 patients in the first month vs. 21 patients in month 6, P<0.05) and biventricular (7 patients in the first month vs. 0 patient in months 4-6, P<0.05) pacemaker recipients.

Conclusions Automatic, daily Home Monitoring of patients treated with cardiac pacemakers allows early detection of AF, and there is a gradual and significant decrease in AF burden.

语种: 英语
WOS记录号: WOS:000327916600004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57742
Appears in Collections:北京大学第一临床医学院_心血管内科_期刊论文

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作者单位: 1.Beijing Hosp, Dept Cardiol, Beijing 100730, Peoples R China
2.Zhejiang Hosp, Dept Cardiol, Hangzhou 310013, Zhejiang, Peoples R China
3.Chinese Acad Med Sci, Fuwai Hosp, Clin EP Lab, Beijing 100037, Peoples R China
4.Chinese Acad Med Sci, Fuwai Hosp, Arrhythm Ctr, Beijing 100037, Peoples R China
5.Peking Union Med Coll, Beijing 100037, Peoples R China
6.Capital Med Univ, Xuan Wu Hosp, Dept Cardiol, Beijing 100053, Peoples R China
7.Harbin Med Univ, Affiliated Hosp 1, Dept Cardiol, Harbin 150001, Heilongjiang, Peoples R China
8.Guangdong Gen Hosp, Dept Cardiol, Guangzhou 510100, Guangdong, Peoples R China
9.Fudan Univ, Zhongshan Hosp, Dept Cardiol, Shanghai 200032, Peoples R China
10.Peking Univ, Hosp 1, Dept Cardiol, Beijing 100034, Peoples R China

Recommended Citation:
Chen Ke-ping,Dai Yan,Hua Wei,et al. Reduction of atrial fibrillation in remotely monitored pacemaker patients: results from a Chinese multicentre registry[J]. CHINESE MEDICAL JOURNAL,2013,126(22):4216-4221.
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