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学科主题: 基础医学
题名:
A microfluidics cytometer for mice anemia detection
作者: Ju, Yanrui1; Song, Jian2; Geng, Zhaoxin1,4; Zhang, Hongze1; Wang, Wei1; Xie, Lide2; Yao, Weijuan3; Li, Zhihong1
刊名: LAB ON A CHIP
发表日期: 2012
DOI: 10.1039/c2lc40332c
卷: 12, 期:21, 页:4355-4362
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemical Research Methods ; Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology
研究领域[WOS]: Biochemistry & Molecular Biology ; Chemistry ; Science & Technology - Other Topics
关键词[WOS]: INTEGRATION ; SYSTEMS
英文摘要:

The design and fabrication of a microfluidic cytometer system and its application for reticulocyte detection are described. This chip can count the target cells, which are focused at the detection window without sheath flow. This cytometer system based on optimized epifluoresence has a competitive advantage in the signal-to-noise ratio. Induced fluorescence from the reticulocyte binded with antibody is detected by the optical module and then transformed into the electronic signal by a photo multiplier tube. After signal processing, the results are automatically read out by a digital module and displayed on the system. To evaluate this microfluidic cytometer system, experiments employing polystyrene (PS) micro beads and induced reticulocyte of mice anemia are carried out, respectively, and the results illustrate that the microfluidic cytometer system is effective in detecting the reticulocyte.

语种: 英语
所属项目编号: 61176111 ; 31170886
项目资助者: National Science Foundation of China
WOS记录号: WOS:000310916100021
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57768
Appears in Collections:基础医学院_北京大学血液流变中心_期刊论文

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作者单位: 1.Chengde Med Coll, Chengde 067000, Hebei Province, Peoples R China
2.Peking Univ, Inst Microelect, Natl Key Lab Sci & Technol Nano Micro Fabricat Te, Beijing 100871, Peoples R China
3.Peking Univ, Hlth Sci Ctr, Dept Physiol & Pathophysiol, Hemorheol Ctr, Beijing 100191, Peoples R China
4.Minzu Univ China, Sch Informat Engn, Beijing 100081, Peoples R China

Recommended Citation:
Ju, Yanrui,Song, Jian,Geng, Zhaoxin,et al. A microfluidics cytometer for mice anemia detection[J]. LAB ON A CHIP,2012,12(21):4355-4362.
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