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学科主题: 临床医学
题名:
The relationship between pulse wave velocity and pulse pressure in chinese patients with essential hypertension
作者: Ni, YB; Wang, HY; Hu, DY; Zhang, WH
关键词: carotid-femoral pulse wave velocity ; arterial stiffness ; essential hypertension
刊名: HYPERTENSION RESEARCH
发表日期: 2003-11-01
卷: 26, 期:11, 页:871-874
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Peripheral Vascular Disease
研究领域[WOS]: Cardiovascular System & Cardiology
关键词[WOS]: STAGE RENAL-DISEASE ; CARDIOVASCULAR RISK ; ARTERIAL DISTENSIBILITY ; STIFFNESS ; MARKER ; URBAN
英文摘要:

Aortic pulse wave velocity (PWV) is a significant and independent predictor of cardiovascular disease in hypertensive subjects and in patients with end-stage renal disease, but there have been few studies on PWV in Chinese patients with essential hypertension. In this cross-sectional study, we investigated 3,156 consecutive patients (mean age: 53.7 +/- 11.58 years) of the Hypertension Division of Ruijin Hospital in Shanghai. Together with sphygmomanometric blood pressure measurements, aortic PWV was measured using a validated automatic device. PWV in patients with pulse pressure (PP) greater than or equal to 60 mmHg was significantly greater than that in patients with PP < 60 mmHg (p < 0.01). PP and PWV were positively related to age (PP: r = 0.396, p = 0.001; PWV: r = 0.531, p = 0.001). After adjustment by age and heart rate, PWV was still closely related to PP (r = 0.249, p = 0.001). At any given systolic blood pressure (SBP), PWV significantly decreased with the increase of diastolic blood pressure (DBP), whereas at any given DBP there was a significant increase of PWV with the increase of SBP. In conclusion, PWV was the major determinant of PP, and was highest in Chinese patients with isolated systolic hypertension, followed by those with systolic and diastolic hypertension, isolated diastolic hypertension, and normal blood pressure.

语种: 英语
WOS记录号: WOS:000187073500001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57796
Appears in Collections:北京大学第二临床医学院_心血管内科_期刊论文

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作者单位: 1.Peking Univ, Peoples Hosp, Dept Cardiol, Beijing 100044, Peoples R China
2.Shanghai Res Inst Hypertens, Cardiovasc Unit, Shanghai 200025, Peoples R China

Recommended Citation:
Ni, YB,Wang, HY,Hu, DY,et al. The relationship between pulse wave velocity and pulse pressure in chinese patients with essential hypertension[J]. HYPERTENSION RESEARCH,2003,26(11):871-874.
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