北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学口腔医学院  > 期刊论文
学科主题: 口腔医学
题名:
Effect of amine functionalization of SBA-15 on controlled baicalin drug release
作者: Wang, Hongsu1; Gao, Xiaohan1; Wang, Yanan1; Wang, Jianfeng1; Niu, Xiaodi1; Deng, Xuliang2
关键词: Sol-gel processes ; SiO2 ; Functional applications ; Biomedical applications
刊名: CERAMICS INTERNATIONAL
发表日期: 2012-12-01
DOI: 10.1016/j.ceramint.2012.05.062
卷: 38, 期:8, 页:6931-6935
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Materials Science, Ceramics
研究领域[WOS]: Materials Science
关键词[WOS]: MESOPOROUS SILICA ; DELIVERY ; MCM-41 ; COPOLYMER ; TRIBLOCK ; SYSTEM ; PORES
英文摘要:

In this paper, we present the release of baicalin from hexagonal periodic mesoporous silica SBA-15 and amino-functionalized mesoporous SBA-15 (A-SBA-15), which serve as drug delivery systems (SBA-15/baicalin and A-SBA-15/baicalin). The modified and drug loaded mesoporous materials were characterized by XRD, SEM, TEM, N-2 physisorption, IR, TG and HPLC. The results demonstrated that slightly higher amount of baicalin was loaded in APS-SBA-15, and the dissolution rate of baicalin from the A-SBA-15/baicalin was much faster than from the SBA-15/baicalin. A-SBA-15/baicalin as baicalin delivery system was better than SBA-15/baicalin because the faster dissolution rate compared with SBA-15/baicalin was more conducive to drug absorption. (C) 2012 Elsevier Ltd and Techna Group S.r.l. All rights reserved.

语种: 英语
所属项目编号: 201 I AA030102 ; 3R211L416604 ; 421031196604 ; 450060445293 ; 801119606201
项目资助者: National High Technology Research and Development program (863 Program) ; Basic Research and Operational Costs of Jilin University, China ; China Postdoctoral Science Foundation
WOS记录号: WOS:000309645000114
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57837
Appears in Collections:北京大学口腔医学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Jilin Univ, Teaching Ctr Basic Courses, Changchun 130062, Peoples R China
2.Peking Univ, Sch & Hosp Stomatol, Dept Geriatr Dent, Beijing 100081, Peoples R China

Recommended Citation:
Wang, Hongsu,Gao, Xiaohan,Wang, Yanan,et al. Effect of amine functionalization of SBA-15 on controlled baicalin drug release[J]. CERAMICS INTERNATIONAL,2012,38(8):6931-6935.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Wang, Hongsu]'s Articles
[Gao, Xiaohan]'s Articles
[Wang, Yanan]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Wang, Hongsu]‘s Articles
[Gao, Xiaohan]‘s Articles
[Wang, Yanan]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace