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学科主题: 临床医学
题名:
The kinetic change of the serum angiogenin level in patients with acute cerebral infarction
作者: Li, Huang; Guo, Huailian; Cheng, Min; Zhao, Yafeng; Jin, Xin
关键词: cerebral infarction ; stroke ; angiogenin ; infarction size ; angiogenesis
刊名: EUROPEAN NEUROLOGY
发表日期: 2007
DOI: 10.1159/000107944
卷: 58, 期:4, 页:224-227
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Neurosciences
研究领域[WOS]: Neurosciences & Neurology
关键词[WOS]: FIBROBLAST-GROWTH-FACTOR ; ISCHEMIC-STROKE ; SERIAL MEASUREMENT ; CARCINOMA ; FOREBRAIN ; PROTEIN ; BRAIN ; CELLS
英文摘要:

Serum angiogenin (ANG) levels were measured with ELISA in 30 cerebral infarction patients at different time points ( within 48 h and on days 3, 7 and 14 after onset of cerebral infarction) and in 20 control subjects. Serum ANG levels in patients were 415.1 +/- 76.8, 410.6 +/- 8 82.1, 443.6 +/- 91.1 and 395.3 +/- 83.9 ng/ml within 48 h and on days 3, 7 and 14 after cerebral infarction, respectively. Serum ANG level in control group was 334.9 +/- 8 93.9 ng/ml. Serum ANG levels were significantly higher in patients with cerebral infarction within 48 h and on days 3 and 7 than in the control group (p < 0.05). Serum ANG level decreased on day 14. Serum ANG levels were significantly higher in patients with large infarction than in those with moderate and small infarction at each time point (p < 0.05). Our observations that serum ANG levels increase significantly in patients with cerebral infarction and the increase in ANG levels correlates with the infarct size suggest that ANG might be involved in the pathophysiologic process of ischemic brain damage. Copyright (c) 2007 S. Karger AG, Basel.

语种: 英语
WOS记录号: WOS:000250655700006
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57891
Appears in Collections:北京大学第二临床医学院_神经内科_期刊论文

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作者单位: 1.Shougang Hosp, Dept Neurol, Beijing, Peoples R China
2.Fuxingh Hosp, Dept Neurol, Beijing, Peoples R China
3.Peking Univ, Peoples Hosp, Dept Neurol, Beijing 100044, Peoples R China

Recommended Citation:
Li, Huang,Guo, Huailian,Cheng, Min,et al. The kinetic change of the serum angiogenin level in patients with acute cerebral infarction[J]. EUROPEAN NEUROLOGY,2007,58(4):224-227.
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