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学科主题临床医学
The kinetic change of the serum angiogenin level in patients with acute cerebral infarction
Li, Huang; Guo, Huailian; Cheng, Min; Zhao, Yafeng; Jin, Xin
关键词Cerebral Infarction Stroke Angiogenin Infarction Size Angiogenesis
刊名EUROPEAN NEUROLOGY
2007
DOI10.1159/000107944
58期:4页:224-227
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Clinical Neurology ; Neurosciences
研究领域[WOS]Neurosciences & Neurology
关键词[WOS]FIBROBLAST-GROWTH-FACTOR ; ISCHEMIC-STROKE ; SERIAL MEASUREMENT ; CARCINOMA ; FOREBRAIN ; PROTEIN ; BRAIN ; CELLS
英文摘要

Serum angiogenin (ANG) levels were measured with ELISA in 30 cerebral infarction patients at different time points ( within 48 h and on days 3, 7 and 14 after onset of cerebral infarction) and in 20 control subjects. Serum ANG levels in patients were 415.1 +/- 76.8, 410.6 +/- 8 82.1, 443.6 +/- 91.1 and 395.3 +/- 83.9 ng/ml within 48 h and on days 3, 7 and 14 after cerebral infarction, respectively. Serum ANG level in control group was 334.9 +/- 8 93.9 ng/ml. Serum ANG levels were significantly higher in patients with cerebral infarction within 48 h and on days 3 and 7 than in the control group (p < 0.05). Serum ANG level decreased on day 14. Serum ANG levels were significantly higher in patients with large infarction than in those with moderate and small infarction at each time point (p < 0.05). Our observations that serum ANG levels increase significantly in patients with cerebral infarction and the increase in ANG levels correlates with the infarct size suggest that ANG might be involved in the pathophysiologic process of ischemic brain damage. Copyright (c) 2007 S. Karger AG, Basel.

语种英语
WOS记录号WOS:000250655700006
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/57891
Collection北京大学第二临床医学院_神经内科
作者单位1.Shougang Hosp, Dept Neurol, Beijing, Peoples R China
2.Fuxingh Hosp, Dept Neurol, Beijing, Peoples R China
3.Peking Univ, Peoples Hosp, Dept Neurol, Beijing 100044, Peoples R China
Recommended Citation
GB/T 7714
Li, Huang,Guo, Huailian,Cheng, Min,et al. The kinetic change of the serum angiogenin level in patients with acute cerebral infarction[J]. EUROPEAN NEUROLOGY,2007,58(4):224-227.
APA Li, Huang,Guo, Huailian,Cheng, Min,Zhao, Yafeng,&Jin, Xin.(2007).The kinetic change of the serum angiogenin level in patients with acute cerebral infarction.EUROPEAN NEUROLOGY,58(4),224-227.
MLA Li, Huang,et al."The kinetic change of the serum angiogenin level in patients with acute cerebral infarction".EUROPEAN NEUROLOGY 58.4(2007):224-227.
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