北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第三临床医学院  > 期刊论文
学科主题: 临床医学
题名:
A systematic review for the antidepressant effects of sleep deprivation with repetitive transcranial magnetic stimulation
作者: Tang, Qing1,2; Li, Guangming3; Wang, Anguo4; Liu, Tao5; Feng, Shenggang6; Guo, Zhiwei1,2; Chen, Huaping1,2; He, Bin1,2; McClure, Morgan A.1,2; Ou, Jun1,2; Xing, Guoqiang7; Mu, Qiwen1,2,8
关键词: Depression ; Sleep deprivation ; Repetitive transcranial magnetic stimulation (rTMS) ; Systematic review
刊名: BMC PSYCHIATRY
发表日期: 2015-11-14
DOI: 10.1186/s12888-015-0674-8
卷: 15
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Psychiatry
研究领域[WOS]: Psychiatry
关键词[WOS]: TREATMENT-RESISTANT DEPRESSION ; DORSOLATERAL PREFRONTAL CORTEX ; TREATING MAJOR DEPRESSION ; RTMS TREATMENT ; DOUBLE-BLIND ; RECEPTOR SENSITIVITY ; UNIPOLAR DEPRESSION ; CONTROLLED-TRIALS ; RANDOMIZED-TRIAL ; HF-RTMS
英文摘要:

Background: Sleep deprivation (SD) and repetitive transcranial magnetic stimulation (rTMS) have been commonly used to treat depression. Recent studies suggest that co-therapy with rTMS and SD may produce better therapeutic effects than either therapy alone. Therefore, this study was to review the current findings to determine if rTMS can augment the therapeutic effects of SD on depression.

Methods: Embase, JSTOR, Medline, PubMed, ScienceDirect, and the Cochrane Central Register of Controlled Trials were searched for clinical studies published between January 1985 and March 2015 using the search term "rTMS/repetitive transcranial magnetic stimulation AND sleep deprivation AND depress*". Only randomized and sham-controlled trials (RCTs) involving the combined use of rTMS and SD in depression patients were included in this systematic review. The scores of the Hamilton Rating Scale for Depression were extracted as primary outcome measures.

Results: Three RCTs with 72 patients that met the inclusion criteria were included for the systematic review. One of the trials reported skewed data and was described alone. The other two studies, which involved 30 patients in the experimental group (SD + active rTMS) and 22 patients in the control group (SD + sham rTMS), reported normally distributed data. The primary outcome measures showed different results among the three publications: two of which showed great difference between the experimental and the control subjects, and the other one showed non-significant antidepressant effect of rTMS on SD. In addition, two of the included studies reported secondary outcome measures with Clinical Global Impression Rating Scale and a self-reported well-being scale which presented good improvement for the depressive patients in the experiment group when compared with the control. The follow-up assessments in two studies indicated maintained results with the immediate measurements.

Conclusions: From this study, an overview of the publications concerning the combined use of rTMS and SD is presented, which provides a direction for future research of therapies for depression. More studies are needed to confirm whether there is an augmentative antidepressant effect of rTMS on SD.

语种: 英语
所属项目编号: 81271559 ; 20155100056 ; 2011HH0017 ; 110616
项目资助者: National Natural Science Foundation of China (NSFC) ; State Administration of Foreign Experts Affairs, the P.R. of China ; Basic Program Funded by Science &amp ; Technology Department of Sichuan Province ; Scientific Research Project of Sichuan Health Department
WOS记录号: WOS:000364626000004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57929
Appears in Collections:北京大学第三临床医学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.North Sichuan Med Univ, Nanchong Cent Hosp, Dept Radiol, Nanchong 637000, Sichuan, Peoples R China
2.Peking Univ, Hosp 3, Beijing 100080, Peoples R China
3.North Sichuan Med Univ, Nanchong Cent Hosp, Imaging Inst Rehabil & Dev Brain Funct, Nanchong 637000, Sichuan, Peoples R China
4.North Sichuan Med Univ, Nanchong Cent Hosp, Dept Oncol, Nanchong 637000, Sichuan, Peoples R China
5.North Sichuan Med Univ, Nanchong Cent Hosp, Dept Urol Surg, Nanchong 637000, Sichuan, Peoples R China
6.North Sichuan Med Univ, Nanchong Cent Hosp, Dept Cardiol, Nanchong 637000, Sichuan, Peoples R China
7.North Sichuan Med Univ, Nanchong Cent Hosp, Dept Nephrol, Nanchong 637000, Sichuan, Peoples R China
8.Johns Hopkins Univ, Lotus Biotech Com LLC, MCC, Rockville, MD 20850 USA

Recommended Citation:
Tang, Qing,Li, Guangming,Wang, Anguo,et al. A systematic review for the antidepressant effects of sleep deprivation with repetitive transcranial magnetic stimulation[J]. BMC PSYCHIATRY,2015,15.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Tang, Qing]'s Articles
[Li, Guangming]'s Articles
[Wang, Anguo]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Tang, Qing]‘s Articles
[Li, Guangming]‘s Articles
[Wang, Anguo]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace