北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 基础医学院  > 神经生物学系  > 期刊论文
学科主题: 基础医学
题名:
Long-duration transcutaneous electric acupoint stimulation alters small-world brain functional networks
作者: Zhang, Yue1; Jiang, Yin2; Glielmi, Christopher B.3; Li, Longchuan3; Hu, Xiaoping3; Wang, Xiaoying4; Han, Jisheng2; Zhang, Jue1; Cui, Cailian2; Fang, Jing1
关键词: Small-world ; Brain functional networks ; Resting-state fMRI ; Long-duration transcutaneous electric acupoint stimulation (TEAS)
刊名: MAGNETIC RESONANCE IMAGING
发表日期: 2013-09-01
DOI: 10.1016/j.mri.2013.01.006
卷: 31, 期:7, 页:1105-1111
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: ORBITOFRONTAL CORTEX ; AFFECTIVE DIMENSION ; ACUPUNCTURE ; FMRI ; PAIN ; CONNECTIVITY ; MECHANISMS ; FREQUENCY ; PERFUSION ; SCHIZOPHRENIA
英文摘要:

Acupuncture, which is recognized as an alternative and complementary treatment in Western medicine, has long shown efficiencies in chronic pain relief, drug addiction treatment, stroke rehabilitation and other clinical practices. The neural mechanism underlying acupuncture, however, is still unclear. Many studies have focused on the sustained effects of acupuncture on healthy subjects, yet there are very few on the topological organization of functional networks in the whole brain in response to long-duration acupuncture (longer than 20 min). This paper presents a novel study on the effects of long-duration transcutaneous electric acupoint stimulation (TEAS) on the small-world properties of brain functional networks. Functional magnetic resonance imaging was used to construct brain functional networks of 18 healthy subjects (9 males and 9 females) during the resting state. All subjects received both TEAS and minimal TEAS (MTEAS) and were scanned before and after each stimulation. An altered functional network was found with lower local efficiency and no significant change in global efficiency for healthy subjects after TEAS, while no significant difference was observed after MTEAS. The experiments also showed that the nodal efficiencies in several paralimbic/limbic regions were altered by TEAS, and those in middle frontal gyrus and other regions by MTEAS. To remove the psychological effects and the baseline, we compared the difference between diffTEAS (difference between after and before TEAS) and diffMTEAS (difference between after and before MTEAS). The results showed that the local efficiency was decreased and that the nodal efficiencies in frontal gyrus, orbitofrontal cortex, anterior cingulate gyrus and hippocampus gyrus were changed. Based on those observations, we conclude that long-duration TEAS may modulate the short-range connections of brain functional networks and also the limbic system. (c) 2013 Elsevier Inc. All rights reserved.

语种: 英语
所属项目编号: 2007CB512501 ; 2009CB522003
项目资助者: National Basic Research Program of China ; Joint Research Project of HSC-COE PKU ; Georgia Tech/Emory University/Peking University seed grant
WOS记录号: WOS:000322944600010
Citation statistics:
内容类型: 期刊论文
版本: 出版稿
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57989
Appears in Collections:基础医学院_神经生物学系_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
Long-duration transcutaneous electric acupoint stimulation alters small-world brain functional networks.pdf(977KB)期刊论文出版稿限制开放 联系获取全文

作者单位: 1.Peking Univ, Coll Engn, Beijing 100871, Peoples R China
2.Peking Univ, Neurosci Res Inst, Beijing 100191, Peoples R China
3.Emory Univ, Georgia Inst Technol, Dept Biomed Engn, Atlanta, GA 30322 USA
4.Peking Univ, Dept Radiol, Hosp 1, Beijing 100871, Peoples R China

Recommended Citation:
Zhang, Yue,Jiang, Yin,Glielmi, Christopher B.,et al. Long-duration transcutaneous electric acupoint stimulation alters small-world brain functional networks[J]. MAGNETIC RESONANCE IMAGING,2013,31(7):1105-1111.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhang, Yue]'s Articles
[Jiang, Yin]'s Articles
[Glielmi, Christopher B.]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhang, Yue]‘s Articles
[Jiang, Yin]‘s Articles
[Glielmi, Christopher B.]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2018  北京大学医学部 - Feedback
Powered by CSpace