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学科主题: 临床医学
题名:
Simultaneous occurrence of hepatitis C virus-associated glomerulonephritis and AL amyloidosis
作者: Cao, Yali; Zhang, Youkang; Wang, Suxia; Zhao, Minghui; Zou, Wanzhong
关键词: AL amyloidosis ; glomerulonephritis ; hepatitis C virus
刊名: NEPHROLOGY DIALYSIS TRANSPLANTATION
发表日期: 2009-09-01
DOI: 10.1093/ndt/gfp296
卷: 24, 期:9, 页:2943-2945
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Transplantation ; Urology & Nephrology
研究领域[WOS]: Transplantation ; Urology & Nephrology
关键词[WOS]: KIDNEY ; INFECTION ; DISEASE
英文摘要:

We report a 65-year-old male with hepatitis C virus (HCV)-associated glomerulonephritis (GN) and AL amyloidosis. This patient had a 14-year history of HCV infection with positive serum HCV RNA at presentation. Diagnosis of HCV-related GN was established using immunohistochemistry in which the HCV-NS3 antigen was mainly detected as granular deposition in glomerular mesangium. AL amyloidosis was determined by electron microscopy, positive Congo red staining and identification of lambda-chain in the kidney specimen and monoclonal IgG-lambda in serum and urine. Under immunoelectron microscopy, the HCV-NS3 antigen was found in electron-dense deposits, while lambda-chains appeared in the amyloid-like filaments.

语种: 英语
WOS记录号: WOS:000269208500054
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58014
Appears in Collections:北京大学第一临床医学院_肾脏内科_期刊论文

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作者单位: Peking Univ, Div Renal, Dept Med,Hosp 1, Key Lab Renal Dis,Minist Hlth China,Inst Nephrol, Beijing 100034, Peoples R China

Recommended Citation:
Cao, Yali,Zhang, Youkang,Wang, Suxia,et al. Simultaneous occurrence of hepatitis C virus-associated glomerulonephritis and AL amyloidosis[J]. NEPHROLOGY DIALYSIS TRANSPLANTATION,2009,24(9):2943-2945.
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