北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学药学院  > 期刊论文
学科主题: 药学
题名:
Preactivation: An Alternative Strategy in Stereoselective Glycosylation and Oligosaccharide Synthesis
作者: Yang, Lin; Qin, Qi; Ye, Xin-Shan
关键词: carbohydrates ; glycosylation ; oligosaccharide synthesis ; preactivation ; stereoselectivity
刊名: ASIAN JOURNAL OF ORGANIC CHEMISTRY
发表日期: 2013
DOI: 10.1002/ajoc.201200136
卷: 2, 期:1, 页:30-49
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Organic
研究领域[WOS]: Chemistry
关键词[WOS]: 4,6-O-BENZYLIDENE-DIRECTED BETA-MANNOPYRANOSYLATION ; NEIGHBORING-GROUP PARTICIPATION ; DIRECT CHEMICAL-SYNTHESIS ; ONE-POT SYNTHESIS ; ANTIGEN GLOBO-H ; ALPHA-SELECTIVE GLYCOSYLATIONS ; HEPARAN-SULFATE PROTEOGLYCANS ; GLYCOSIDE-BOND FORMATION ; PRE-ACTIVATION PROTOCOL ; 1,2-CIS O-GLYCOSYLATION
英文摘要:

The multifaceted biological importance of carbohydrates has made them very popular targets in modern synthetic chemistry. Great progress has been made in stereoselective glycosylation methods and the construction of complex oligosaccharides. This Focus Review highlights the versatile applications of preactivation strategies in stereoselective glycosylation and oligosaccharide synthesis. Recent advances in synthetic methods, such as 4,6-O-benzylidene-acetal-directed beta-mannosylation, the 1,2-cis-glycosylation mediated by a chiral auxiliary, the use of an oxazolidinone or carbonate protecting group, and glycosylation with participating additives, are described. Various examples of sequential glycosylation based on preactivation protocols for efficient oligosaccharide assembly are also summarized.

语种: 英语
所属项目编号: 2012ZX09502001-001 ; 2012CB822100
项目资助者: Ministry of Science and Technology of China
WOS记录号: WOS:000325949000002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58042
Appears in Collections:北京大学药学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

Recommended Citation:
Yang, Lin,Qin, Qi,Ye, Xin-Shan. Preactivation: An Alternative Strategy in Stereoselective Glycosylation and Oligosaccharide Synthesis[J]. ASIAN JOURNAL OF ORGANIC CHEMISTRY,2013,2(1):30-49.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Yang, Lin]'s Articles
[Qin, Qi]'s Articles
[Ye, Xin-Shan]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Yang, Lin]‘s Articles
[Qin, Qi]‘s Articles
[Ye, Xin-Shan]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2018  北京大学医学部 - Feedback
Powered by CSpace