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学科主题: 临床医学
题名:
Mammary ductoscopy and follow-up avoid unnecessary duct excision in patients with pathologic nipple discharge
作者: Liu, Miao; Guo, Giagia; Xie, Fei; Wang, Siyuan; Yang, Houpu; Wang, Shu
关键词: ductoscopy ; nipple discharge ; duct excision ; mammary
刊名: JOURNAL OF SURGICAL ONCOLOGY
发表日期: 2015-08-01
DOI: 10.1002/jso.23972
卷: 112, 期:2, 页:139-143
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology ; Surgery
研究领域[WOS]: Oncology ; Surgery
关键词[WOS]: INTRADUCTAL PROLIFERATIONS ; STANDARD METHODS ; BREAST ; MANAGEMENT ; WOMEN ; DIAGNOSIS ; PAPILLOMAS ; EXPERIENCE ; ENDOSCOPY ; CANCER
英文摘要:

Background and ObjectivesThe goal of this study was to evaluate the efficacy of ductoscopy and follow-up for the diagnoses of intraductal lesions and the concomitant advantages of avoiding surgery for patients with pathologic nipple discharge (PND).

MethodsTwo hundred and sixty-six ductoscopies were performed for 238 women. Patients with positive ductoscopies underwent surgery. If no positive lesions were present upon ductoscopy, the women were followed.

ResultsOf 266 ductoscopic examinations, 168 (63.2%, 168/266) breasts from 165 patients were found to have positive images. The final histopathological results revealed that 93 patients with intraductal papilloma, 42 with intraductal papillomatosis, 15 with ADH lesions, DCIS in 9 patients, 1 case with invasive ductal carcinoma (IDC), 6 cases with duct ectasia, and 2 cases with inflammation. Seventy-three patients with negative results upon ductoscopy were followed with a median time of 48 months. Twelve patients had PND recurrence and were diagnosed as papilloma or papillomatosis based on pathology after surgery. PND disappeared for 51 patients after ductoscopy, and no recurrence or disease evolvement was founded for them.

ConclusionDuctoscopy and follow-up were advantageous for selecting patients to undergo surgery or surveillance. The recurrence of PND after ductoscopy might be a strong predictor for having intraductal disease. J. Surg. Oncol. 2015 111:139-143. (c) 2015 Wiley Periodicals, Inc.

语种: 英语
WOS记录号: WOS:000360094300004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58056
Appears in Collections:北京大学第二临床医学院_乳腺外科_期刊论文

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作者单位: Peking Univ, Breast Ctr, Peoples Hosp, Beijing 100044, Peoples R China

Recommended Citation:
Liu, Miao,Guo, Giagia,Xie, Fei,et al. Mammary ductoscopy and follow-up avoid unnecessary duct excision in patients with pathologic nipple discharge[J]. JOURNAL OF SURGICAL ONCOLOGY,2015,112(2):139-143.
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