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学科主题: 精神卫生
题名:
A diffusion tensor imaging study of middle and superior cerebellar peduncle in male patients with schizophrenia
作者: Wang, F; Sun, ZG; Du, XK; Wang, XL; Cong, Z; Zhang, HY; Zhang, D; Hong, N
关键词: diffusion tensor imaging ; superior cerebellar peduncle ; middle cerebellar peduncle ; schizophrenia ; fractional anisotropy ; averaged diffusion coefficient
刊名: NEUROSCIENCE LETTERS
发表日期: 2003-09-18
DOI: 10.1016/S0304-3940(03)00589-5
卷: 348, 期:3, 页:135-138
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Neurosciences
研究领域[WOS]: Neurosciences & Neurology
关键词[WOS]: COGNITIVE DYSMETRIA ; WHITE-MATTER ; MRI ; MORPHOLOGY ; CIRCUITRY ; PSYCHOSIS ; FEATURES ; TISSUES
英文摘要:

Many studies have confirmed that the cerebellum takes part in higher-order cognitive coordination; profound fibers projecting to and from the cerebellum underlie its cognitive function. Since the superior and middle cerebellar peduncles are the main pathways of neural fibers in the cerebellum, these structures became the focus of our interest in evaluating the cognitive dysfunction reported in schizophrenia. Diffusion tensor imaging (DTI) was used to examine the anatomical integrity of the neural fibers in the superior and middle cerebellar peduncles. DTI was performed on 29 patients and 20 normal controls; we subsequently calculated the fractional anisotropy and mean diffusivity in these regions. Statistical analysis revealed that there was no significant difference between patients with schizophrenia and our matched control group. No structural abnormalities were detected in the white matter of the superior and middle cerebellar peduncles. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

语种: 英语
WOS记录号: WOS:000184972200003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58070
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Peking Univ, Inst Mental Hlth, Beijing 100083, Peoples R China
2.Peking Univ, Peoples Hosp, Dept Radiol, Beijing 100044, Peoples R China

Recommended Citation:
Wang, F,Sun, ZG,Du, XK,et al. A diffusion tensor imaging study of middle and superior cerebellar peduncle in male patients with schizophrenia[J]. NEUROSCIENCE LETTERS,2003,348(3):135-138.
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