IR@PKUHSC  > 北京大学临床肿瘤学院  > 超声科
学科主题临床医学
The role of contrast-enhanced ultrasound on the diagnosis of small hepatocellular carcinoma (<= 3 cm) in patients with cirrhosis
Chen, Min Hua; Dai, Ying; Yan, Kun; Fan, Zhi Hui; Yin, Shan Shan; Yang, Wei; Wu, Wei; Wang, Yan Bin; Li, Ji You
关键词Ultrasound Contrast Agent Cirrhosis Hepatocellular Carcinoma Small Lesion
刊名HEPATOLOGY RESEARCH
2006-08-01
DOI10.1016/j.hepres.2006.04.013
35期:4页:281-288
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Gastroenterology & Hepatology
研究领域[WOS]Gastroenterology & Hepatology
关键词[WOS]FOCAL LIVER-LESIONS ; DYSPLASTIC NODULES ; HEPATIC-TUMORS ; AGENT ; ULTRASONOGRAPHY ; PATTERNS ; CT ; US
英文摘要

Background: This study aimed to investigate the diagnostic value of contrast-enhanced ultrasound (CEUS) of small hepatocellular carcinomas (HCC) (<= 3cm) in patient with cirrhosis.

Materials and methods: Fifty-seven cases with 64 small HCC tumors (<= 3cm) were analyzed in this study. In these cases, all patients had liver cirrhosis and surgical or biopsy histopathological diagnosis. Diagnosis of baseline ultrasound (US) and CEUS of each lesion was made separately using a 5-point scoring system based on the US and CEUS characteristics of the lesions and was compared with histopathological results.

Results: All of the 47 moderately to poorly differentiated (MD-PD) HCC presented the "fast-in and fast-out" (FIFO) pattern with fast enhancement within 25 s and then a quick wash-out within 90 s after contrast injection. Ten of 17 well-differentiated (WD) HCC (58.8%) had "fast-in and slow-out" (FISO) pattern which washed out after 90 s and I WD HCC had "fast-in and no-out" (FINO) pattern which did not wash out till 360 s. Three well differentiated clear cell carcinomas smaller than 1.5 cm showed "slow-in and slow-out" (SISO) pattern which enhanced after 25 s and washed out after 90 s. On baseline US, only 36 lesions (56.3%) were diagnosed as definitely or possibly malignant lesions. After CEUS, 50 lesions (78.1%) with "FIFO" pattern were diagnosed as definitely malignant, while 15.6% (10 lesions) with "FISO" pattern as possibly malignant, only 4 lesions (6.3%) with "FINO" or "SISO" pattern could not be diagnosed by CEUS.

Conclusion: The typical enhancement patterns of "FIFO" or "FISO" of small HCC could improve the diagnostic ability of ultrasound in cirrhotic liver. Small HCC also had atypical enhancement patterns including "FINO" and "SISO". It shows that CEUS could be a useful imaging modality in small HCC diagnosis. (c) 2006 Elsevier Ireland Ltd. All rights reserved.

语种英语
WOS记录号WOS:000240159300010
引用统计
被引频次:19[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/58140
专题北京大学临床肿瘤学院_超声科
作者单位1.Peking Univ, Sch Oncol, Dept Ultrasound, Beijing 100036, Peoples R China
2.Peking Univ, Sch Oncol, Dept Pathol, Beijing 100036, Peoples R China
推荐引用方式
GB/T 7714
Chen, Min Hua,Dai, Ying,Yan, Kun,et al. The role of contrast-enhanced ultrasound on the diagnosis of small hepatocellular carcinoma (<= 3 cm) in patients with cirrhosis[J]. HEPATOLOGY RESEARCH,2006,35(4):281-288.
APA Chen, Min Hua.,Dai, Ying.,Yan, Kun.,Fan, Zhi Hui.,Yin, Shan Shan.,...&Li, Ji You.(2006).The role of contrast-enhanced ultrasound on the diagnosis of small hepatocellular carcinoma (<= 3 cm) in patients with cirrhosis.HEPATOLOGY RESEARCH,35(4),281-288.
MLA Chen, Min Hua,et al."The role of contrast-enhanced ultrasound on the diagnosis of small hepatocellular carcinoma (<= 3 cm) in patients with cirrhosis".HEPATOLOGY RESEARCH 35.4(2006):281-288.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Chen, Min Hua]的文章
[Dai, Ying]的文章
[Yan, Kun]的文章
百度学术
百度学术中相似的文章
[Chen, Min Hua]的文章
[Dai, Ying]的文章
[Yan, Kun]的文章
必应学术
必应学术中相似的文章
[Chen, Min Hua]的文章
[Dai, Ying]的文章
[Yan, Kun]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。