|Exposures to PM2.5 components and heart rate variability in taxi drivers around the Beijing 2008 Olympic Games|
|Wu, Shaowei1; Deng, Furong1; Niu, Jie2; Huang, Qinsheng2; Liu, Youcheng3; Guo, Xinbiao1|
|关键词||Air Pollution Cardiac Autonomic Function Epidemiology Heart Rate Variability Particulate Matter Traffic|
|刊名||SCIENCE OF THE TOTAL ENVIRONMENT|
|WOS标题词||Science & Technology|
|研究领域[WOS]||Environmental Sciences & Ecology|
|关键词[WOS]||ATMOSPHERIC PARTICULATE MATTER ; AIR-POLLUTION ; CARDIOVASCULAR-DISEASES ; PERSONAL EXPOSURE ; AMBIENT AIR ; CHINA ; ASSOCIATION ; PARTICLES ; METALS ; INHALATION|
Background: Carbonaceous and metallic components of particles have been shown to play a role in particles′ effects on cardiac autonomic function as measured by heart rate variability (HRV). Previously we reported the association of HRV with marked changes in traffic-related particulate air pollution around the Beijing 2008 Olympic Games in a panel of taxi drivers.
Objective: We further investigated the relationship between exposures to the carbonaceous and metallic components of traffic-related particles and HRV in the same population.
Methods: Repeated measurements of in-car exposures to particulate matter <= 2.5 jam in aerodynamic diameter (PM2.5), carbon monoxide and nitrogen oxides were conducted in a group of 14 taxi drivers for one work shift in four study periods around the Beijing 2008 Olympics. The quantities of organic/elemental carbons and 27 elements of the in-car PM2.5 mass were determined laboratorially. Linear mixed-effects models were used to evaluate the impact of exposures to different PM2.5 components on HRV while controlling for potential confounders.
Results: Taxi drivers′ exposures to in-car PM2.5 and its components showed dramatic changes across the four study periods around the Beijing 2008 Olympics. Differences in associations of in-car PM2.5 components with HRV were found. An interquartile range (IQR: 917.9 ng/m(3)) increase in calcium was associated with a 5.48 millisecond [ms, 95% confidence interval (CI): 0.71. 10.24] increase in standard deviations of normal-to-normal (SDNN) intervals, while an IQR (4.1 ng/m(3)) increase in nickel was associated with a 1.53 ms (95% CI: 0.14, 2.92) increase in SDNN index. Additionally, a decline of 8.11 ms (95% CI: -15.26, -0.97) in SDNN per IQR (481.4 ng/m(3)) increase in iron was also found.
Conclusion: The results support associations of PM2.5 metallic components with HRV in younger healthy individuals. Future studies are needed to clarify the interaction among different PM2.5 components or the role of PM2.5 mixtures. (C) 2011 Elsevier B.V. All rights reserved.
|项目编号||2006BAI19B06 ; 81072267|
|资助机构||National Key Technologies R& ; D Program of China ; National Natural Science Foundation of China|
|作者单位||1.Peking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth Sci, Beijing 100191, Peoples R China|
2.Peking Univ, Hosp 3, Beijing 100191, Peoples R China
3.Univ N Texas Hlth Sci Ctr, Sch Publ Hlth, Dept Environm & Occupat Hlth Sci, Ft Worth, TX USA
|Wu, Shaowei,Deng, Furong,Niu, Jie,et al. Exposures to PM2.5 components and heart rate variability in taxi drivers around the Beijing 2008 Olympic Games[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2011,409(13):2478-2485.|
|APA||Wu, Shaowei,Deng, Furong,Niu, Jie,Huang, Qinsheng,Liu, Youcheng,&Guo, Xinbiao.(2011).Exposures to PM2.5 components and heart rate variability in taxi drivers around the Beijing 2008 Olympic Games.SCIENCE OF THE TOTAL ENVIRONMENT,409(13),2478-2485.|
|MLA||Wu, Shaowei,et al."Exposures to PM2.5 components and heart rate variability in taxi drivers around the Beijing 2008 Olympic Games".SCIENCE OF THE TOTAL ENVIRONMENT 409.13(2011):2478-2485.|