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学科主题: 药学
题名:
Trends and problems in studies of rare-earths-based drugs
作者: Yang Xiaogai; Yang Xiaoda; Wang Kui
关键词: rare earths ; biological effects ; therapeutic agents
刊名: PROGRESS IN CHEMISTRY
发表日期: 2007-03-01
卷: 19, 期:2-3, 页:203-206
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
关键词[WOS]: MEDICINAL INORGANIC-CHEMISTRY ; CERIUM NITRATE ; NIH 3T3-CELLS ; LANTHANUM ; BURNS ; MICE ; RAT
英文摘要:

The interest on the studies of rare-earths-based drugs is increasing. The recent issue of Chemical Society Reviews is a special issue devoting to the current studies in this aspect. In the present comment, the trends and problems are discussed in connection with the current status in this field and the reviews published in the Chemical Society Reviews. The basic problems open for clarification are emphasized. Enlightened by the changing research paradigm for drug exploration, the following working principles are discussed: to convert the adverse biological effects to the pharmacological ones, to lay the basis of study on the intervention on cell signaling networks, to handle the activity-toxicity relationship and the strategies for rational design.

语种: 中文
WOS记录号: WOS:000245139600001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58161
Appears in Collections:北京大学药学院_化学生物学系_期刊论文

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作者单位: Peking Univ, Dept Biol Chem, Sch Pharmaceut Sci, Hlth Sci Ctr, Beijing 100083, Peoples R China

Recommended Citation:
Yang Xiaogai,Yang Xiaoda,Wang Kui. Trends and problems in studies of rare-earths-based drugs[J]. PROGRESS IN CHEMISTRY,2007,19(2-3):203-206.
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