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学科主题: 临床医学
题名:
Use of microperimetry to compare macular light sensitivity in eyes with open-angle and angle-closure glaucoma
作者: Huang, Ping1; Shi, Yan1; Wang, Xin1; Zhang, Samuel Shao-Min2; Zhang, Chun1
关键词: Microperimetry ; CACG ; POAG ; Macular function
刊名: JAPANESE JOURNAL OF OPHTHALMOLOGY
发表日期: 2012-03-01
DOI: 10.1007/s10384-011-0111-6
卷: 56, 期:2, 页:138-144
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Ophthalmology
研究领域[WOS]: Ophthalmology
关键词[WOS]: OPTICAL COHERENCE TOMOGRAPHY ; VISUAL-FIELD ; FUNDUS PERIMETRY ; NORMAL INDIVIDUALS ; CAPILLARY DENSITY ; NERVE HEAD ; HYPERTENSION ; TOPOGRAPHY ; NEUROPATHY ; THRESHOLD
英文摘要:

Use of microperimetry to compare macular light sensitivity in early and moderate primary open-angle glaucoma (POAG), chronic angle-closure glaucoma (CACG), and normal controls.

A cross-sectional, case-control, comparative study. A total of 126 eyes from 126 subjects, 53 normal eyes, 50 POAG eyes, and 23 CACG eyes were studied. A macular 10A degrees program was performed with MP-1 microperimetry. The mean sensitivities (MS) of the central 2A degrees, 6A degrees, and 10A degrees visual fields were compared among the POAG, CACG, and normal controls. The mean light sensitivities of the four quadrants in the central 6A degrees were also analyzed in each group.

The MS of the central 2A degrees, 6A degrees, 10A degrees, and total macular areas in the POAG patients were significantly reduced compared with those for the normal controls (all P < 0.05). The MS of the central 6A degrees, 10A degrees, and total areas, except those at the central 2A degrees, in the CACG patients were significantly reduced. In the central 6A degrees, more severe loss of MS was observed in the inferotemporal quadrant in the POAG group. In the CACG group, the reduction in the MS among the four quadrants was not significantly different (P = 0.623).

Different patterns of macular function damage were identified in both early and moderate stage POAG and in CACG patients.

语种: 英语
项目资助者: Pfizer Investment Co., Ltd., Beijing, China
WOS记录号: WOS:000301485300006
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58226
Appears in Collections:北京大学第三临床医学院_眼科_期刊论文

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作者单位: 1.Peking Univ, Dept Ophthalmol, Hosp 3, Key Lab Vis Loss & Restorat,Minist Educ, Beijing 100191, Peoples R China
2.Penn State Univ, Coll Med, Penn State Hershey Eye Ctr, Dept Neural & Behav Sci, Hershey, PA 17033 USA

Recommended Citation:
Huang, Ping,Shi, Yan,Wang, Xin,et al. Use of microperimetry to compare macular light sensitivity in eyes with open-angle and angle-closure glaucoma[J]. JAPANESE JOURNAL OF OPHTHALMOLOGY,2012,56(2):138-144.
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