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学科主题: 临床医学
题名:
Effects of nitric oxide synthase inhibitor to esophagus in a feline esophagitis model
作者: Liu, B
关键词: esophageal motility ; esophagitis ; L-NNA ; nitric oxide synthase inhibitor
刊名: DISEASES OF THE ESOPHAGUS
发表日期: 2003
卷: 16, 期:4, 页:312-314
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology
研究领域[WOS]: Gastroenterology & Hepatology
关键词[WOS]: SPHINCTER ; CAT
英文摘要:

The present study explores the effects of nitric oxide synthase inhibitor on esophageal motility in a feline model with esophagitis. Perfusion of the esophagus with acid produced inflammatory changes of esophageal mucosa. The esophageal motility was measured before and after the perfusion. One group of cats was given nitric oxide inhibitor orally at the same time as the perfusion of acid. The control group was given water instead. Esophagitis impairs the motility of the esophagus. However, the esophageal motility of the cats that were given nitric oxide synthase inhibitor decreased less than that of the control group. The results suggested that during esophagitis there is an alteration of the nitric oxide synthase/nitric oxide pathway in the esophagus, which may be one of the important mechanisms of esophageal motility dysfunction.

语种: 英语
WOS记录号: WOS:000186869900008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58238
Appears in Collections:北京大学第一临床医学院_消化内科_期刊论文

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作者单位: Beijing Univ, Hosp 1, Dept Gastroenterol, Beijing 100034, Peoples R China

Recommended Citation:
Liu, B. Effects of nitric oxide synthase inhibitor to esophagus in a feline esophagitis model[J]. DISEASES OF THE ESOPHAGUS,2003,16(4):312-314.
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