IR@PKUHSC  > 北京大学第一临床医学院  > 消化科
学科主题临床医学
Effects of nitric oxide synthase inhibitor to esophagus in a feline esophagitis model
Liu, B
关键词esophageal motility esophagitis L-NNA nitric oxide synthase inhibitor
刊名DISEASES OF THE ESOPHAGUS
2003
16期:4页:312-314
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Gastroenterology & Hepatology
研究领域[WOS]Gastroenterology & Hepatology
关键词[WOS]SPHINCTER ; CAT
英文摘要

The present study explores the effects of nitric oxide synthase inhibitor on esophageal motility in a feline model with esophagitis. Perfusion of the esophagus with acid produced inflammatory changes of esophageal mucosa. The esophageal motility was measured before and after the perfusion. One group of cats was given nitric oxide inhibitor orally at the same time as the perfusion of acid. The control group was given water instead. Esophagitis impairs the motility of the esophagus. However, the esophageal motility of the cats that were given nitric oxide synthase inhibitor decreased less than that of the control group. The results suggested that during esophagitis there is an alteration of the nitric oxide synthase/nitric oxide pathway in the esophagus, which may be one of the important mechanisms of esophageal motility dysfunction.

语种英语
WOS记录号WOS:000186869900008
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/58238
专题北京大学第一临床医学院_消化科
作者单位Beijing Univ, Hosp 1, Dept Gastroenterol, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Liu, B. Effects of nitric oxide synthase inhibitor to esophagus in a feline esophagitis model[J]. DISEASES OF THE ESOPHAGUS,2003,16(4):312-314.
APA Liu, B.(2003).Effects of nitric oxide synthase inhibitor to esophagus in a feline esophagitis model.DISEASES OF THE ESOPHAGUS,16(4),312-314.
MLA Liu, B."Effects of nitric oxide synthase inhibitor to esophagus in a feline esophagitis model".DISEASES OF THE ESOPHAGUS 16.4(2003):312-314.
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