IR@PKUHSC  > 北京大学精神卫生研究所
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Prospective memory in schizophrenia: Further clarification of nature of impairment
Wang, Ya2,3; Chan, Raymond C. K.1,2,4; Hong, Xiaohong5; Ma, Zheng6; Yang, Tianxiao2; Guo, Lan3; Yu, Xin7; Li, Zhanjiang6; Yuan, Yanbo7; Gong, Qi-yong8; Shum, David9
关键词Schizophrenia Prospective memory Neurocognitive function Cue detection
刊名SCHIZOPHRENIA RESEARCH
2008-10-01
DOI10.1016/j.schres.2008.07.002
105期:1-3页:114-124
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Psychiatry
资助者Suit Yat-Sen University ; Institute of Psychology, Chinese Academy of Sciences ; National Basic Research Programme ; Suit Yat-Sen University ; Institute of Psychology, Chinese Academy of Sciences ; National Basic Research Programme
研究领域[WOS]Psychiatry
关键词[WOS]WORKING-MEMORY ; PREFRONTAL CORTEX ; DYSFUNCTION ; METAANALYSIS ; COMPONENTS ; DEFICITS ; REGIONS ; SCALE ; FMRI
英文摘要

Prospective memory (PM) refers to the ability to execute a delayed intention and is different from retrospective memory (RM) in its nature and underlying mechanism (e.g., intention formation, maintenance, detection of PM cue and intention execution). Although preliminary studies have found PM impairment in patients with schizophrenia, the nature and magnitude of this problem in this clinical group is not yet fully known. The current study aimed to further clarify the nature of this impariment in schizophrenia. Fifty-four patients with schizophrenia and fifty-four healthy volunteers matched on demographic variables, IQ and executive functions took part in the study. Time-, event-, and activity-based PM tasks and a set of neurocognitive tests were administered to the participants. Results showed that patients with schizophrenia performed significantly worse on all sub-types of PM tasks, even after controlling for neurocognitive functions such as working memory, verbal memory, visual memory, and executive function. These findings suggest PM deficit is a primary deficit rather than a secondary consequence of neurocognitive impairments in schizophrenia. Analysis found that PM deficits may be mainly due to the impairment of the cue detection and intention retrieval stage. (c) 2008 Elsevier B.V. All rights reserved.

语种英语
所属项目编号O7CX031003 ; KSCX2-YW-R-131 ; 2007CB512305
资助者Suit Yat-Sen University ; Institute of Psychology, Chinese Academy of Sciences ; National Basic Research Programme ; Suit Yat-Sen University ; Institute of Psychology, Chinese Academy of Sciences ; National Basic Research Programme
WOS记录号WOS:000260591900013
Citation statistics
Cited Times:30[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/58261
Collection北京大学精神卫生研究所
作者单位1.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China
2.Sun Yat Sen Univ, Dept Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Guangzhou 510275, Guangdong, Peoples R China
3.Sun Yat Sen Univ, Sch Life Sci, Guangzhou 510275, Guangdong, Peoples R China
4.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
5.Shantou Univ, Mental Hlth Ctr, Shantou, Peoples R China
6.Beijing Anding Hosp, Beijing, Peoples R China
7.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
8.Sichuan Univ, W China Hosp, W China Sch Med, Dept Radiol,Huaxi MR Res Ctr, Chengdu 610064, Peoples R China
9.Griffith Univ, Griffith Inst Hlth & Med Res, Brisbane, Qld 4111, Australia
Recommended Citation
GB/T 7714
Wang, Ya,Chan, Raymond C. K.,Hong, Xiaohong,et al. Prospective memory in schizophrenia: Further clarification of nature of impairment[J]. SCHIZOPHRENIA RESEARCH,2008,105(1-3):114-124.
APA Wang, Ya.,Chan, Raymond C. K..,Hong, Xiaohong.,Ma, Zheng.,Yang, Tianxiao.,...&Shum, David.(2008).Prospective memory in schizophrenia: Further clarification of nature of impairment.SCHIZOPHRENIA RESEARCH,105(1-3),114-124.
MLA Wang, Ya,et al."Prospective memory in schizophrenia: Further clarification of nature of impairment".SCHIZOPHRENIA RESEARCH 105.1-3(2008):114-124.
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