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学科主题临床医学
Pulse Wave Velocity as a Marker of Cognitive Impairment in the Elderly
Scuteri, Angelo1; Wang, HongYu2
关键词Arterial aging arterial stiffness cognition dementia marker prevention pulse wave velocity
刊名JOURNAL OF ALZHEIMERS DISEASE
2014
DOI10.3233/JAD-141416
suppl.4页:S401-S410
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Neurosciences
研究领域[WOS]Neurosciences & Neurology
关键词[WOS]BLOOD-PRESSURE LEVELS ; END-ORGAN DAMAGE ; ARTERIAL STIFFNESS ; ALZHEIMERS-DISEASE ; HYPERTENSIVE PATIENTS ; METABOLIC SYNDROME ; OLDER SUBJECTS ; RISK-FACTORS ; MEMORY LOSS ; DEMENTIA
英文摘要

Carotid-femoral pulse wave velocity (PWV), an index of large artery stiffness, is a good proxy of arterial aging and also an independent marker of cardiovascular disease. A consistently growing number of studies has shown a significant inverse association of arterial aging and cognitive function: the greater the PWV, the lower the cognitive performance (and the greater its decline over time)-regardless of heterogeneity in study populations, sample size, and measure of cognitive functions adopted in each study. Therefore the epidemiological evidence and the biological plausibility require adoption of strategies to foster the routine measurement of PWV and cognitive function measurements in each and every older subject, particularly those at higher cardiovascular risk. Consistently, limited available healthcare resources should be progressively shifted from a sterile differential diagnosis between Alzheimer-type and vascular dementia to interventions aimed to reduce PWV and, thus, to prevent dementia before its onset or to decrease its rate of progression.

语种英语
WOS记录号WOS:000343893000009
引用统计
被引频次:24[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/58298
专题北京大学首钢医院_心血管内科
作者单位1.Hosp San Raffaele Pisana, IRCCS, Rome, Italy
2.Peking Univ, Shougang Hosp, Dept Vasc Med, Beijing 100871, Peoples R China
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GB/T 7714
Scuteri, Angelo,Wang, HongYu. Pulse Wave Velocity as a Marker of Cognitive Impairment in the Elderly[J]. JOURNAL OF ALZHEIMERS DISEASE,2014,suppl.4:S401-S410.
APA Scuteri, Angelo,&Wang, HongYu.(2014).Pulse Wave Velocity as a Marker of Cognitive Impairment in the Elderly.JOURNAL OF ALZHEIMERS DISEASE,suppl.4,S401-S410.
MLA Scuteri, Angelo,et al."Pulse Wave Velocity as a Marker of Cognitive Impairment in the Elderly".JOURNAL OF ALZHEIMERS DISEASE suppl.4(2014):S401-S410.
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