IR@PKUHSC  > 北京大学药学院
学科主题药学
Stereoselective transacetalization of 1,1,3,3-tetramethoxypropane and N-benzoylaminodiols
Bi, LR; Zhao, M; Wang, C; Peng, SQ
关键词asymmetric synthesis transacetalization antitumor agents 2,5-disubstituted-1,3-dioxanes amino alcohols
刊名EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
2000-07-01
14页:2669-2676
收录类别IC ; CCR ; SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Organic
研究领域[WOS]Chemistry
英文摘要

The trans acetalization of 1,1,3,3 -tetramethoxypropane and an N-benzoylaminodiol provided stereoselectively the corresponding 2,5-disubstituted-1,3-dioxanes. The stereochemistry of the rings formed in the transacetalization depended on the structure of the amino diol, and the ratio of the products depended on the reaction conditions, as expected. This kind of stereoselective transacetalization not only gives a series of useful building blocks but also generates interesting 1,3-dioxanes which target protein kinase C.

语种英语
WOS记录号WOS:000088368800019
Citation statistics
Cited Times:17[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/58355
Collection北京大学药学院
作者单位Beijing Med Univ, Coll Pharmaceut Sci, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Bi, LR,Zhao, M,Wang, C,et al. Stereoselective transacetalization of 1,1,3,3-tetramethoxypropane and N-benzoylaminodiols[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2000(14):2669-2676.
APA Bi, LR,Zhao, M,Wang, C,&Peng, SQ.(2000).Stereoselective transacetalization of 1,1,3,3-tetramethoxypropane and N-benzoylaminodiols.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY(14),2669-2676.
MLA Bi, LR,et al."Stereoselective transacetalization of 1,1,3,3-tetramethoxypropane and N-benzoylaminodiols".EUROPEAN JOURNAL OF ORGANIC CHEMISTRY .14(2000):2669-2676.
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