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学科主题: 临床医学
题名:
The prevalence of erectile dysfunction among subjects with late-onset hypogonadism: a population-based study in China
作者: Tang, Wen-Hao1; Zhuang, Xin-Jie2; Shu, Ru-Ming3; Guan, Di4; Ji, Yu-Dang5; Zhang, Bao-Long5; Wang, Can-Gang5; Zhuang, Li-Hua5; Yang, Zhuo2; Hong, Kai1; Ma, Lu-Lin1; Jiang, Hui1; Zhou, Shan-Jie6,7; Gu, Yi-Qun7
关键词: Erectile dysfunction ; late-onset hypogonadism in males ; prevalence rate ; aging male ; community population
刊名: INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
发表日期: 2015
卷: 8, 期:8, 页:13901-13910
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, Research & Experimental
研究领域[WOS]: Research & Experimental Medicine
关键词[WOS]: INTERNATIONAL INDEX ; ANDROGEN DEFICIENCY ; NATIONAL-HEALTH ; SYMPTOMS ; MEN ; TESTOSTERONE ; MALES ; OLD
英文摘要:

Introduction: The concurrence of chronic diseases and some well-defined risk factors significantly impacts the prevalence of erectile dysfunction (ED). Aim: To determine whether late-onset hypogonadism (LOH) impacts the prevalence of ED using investigation reproductive health data of middle-aged and aging males in China. Methods: The reproductive health status of 1498 males, aged 40-69 years, was evaluated using questionnaires of LOH based on the Androgen Deficiency in Aging Males (ADAM) and Aging Male Symptoms scale (AMS), as well as the International Index of Erectile Function-5 (IIEF-5) assessment. The 10th percentile of serum total testosterone (TT) and calculated free testosterone (cFT) levels of controls were set as cut-off levels of AD. The main outcome measures were used to assess the prevalence of LOH and ED according to different subject characteristics. Results: Of the 1472 subjects who completed the questionnaires who supplied hormone measurements, the prevalence of self-reported ED and identified by the IIEF-5 assessment were 11.28% and 77.85%, respectively. The IIEF-5 assessment revealed a prevalence of ED of 55.34%, 88.20%, and 91.77%, respectively, among those aged 40-49, 50-59, and 60-69 years. AD rates of ED subjects were 13.73% and 40.69% according to the TT and cFT cut-off levels. The prevalence of ED among subjects positive for LOH (ADAM+ and AMS+) were 88.81% and 95.80%, respectively. The prevalence of ED among the AD subjects (TT and cFT cut-off levels) with LOH (ADAM+ and AMS+) were 86.67%/81.82%. And the prevalence of ED among clinical LOH subjects (ADAM+ and AMS+) were 89.51%/98.48%. Conclusions: We found that middle-aged and aging Chinese males were at a relatively high risk of ED. The prevalence of ED among subjects with LOH symptoms was greater than in all recruited subjects. The effect of LOH on the prevalence of ED far outweighed the risk of decreased testosterone levels.

语种: 英语
所属项目编号: 2007JZ01
项目资助者: State-Level Special Commonweal Research Project
WOS记录号: WOS:000365271900248
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58365
Appears in Collections:北京大学第三临床医学院_泌尿外科_期刊论文

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作者单位: 1.Peking Univ, Dept Urol, Hosp 3, Beijing 100191, Peoples R China
2.Peking Univ, Reprod Med Ctr, Hosp 3, Beijing 100191, Peoples R China
3.First Hosp Nanchang, Dept Obstet & Gynaecol, Nanchang 330008, Peoples R China
4.Capital Med Univ, Beijing Tongren Hosp, Dept Urol, Beijing 100730, Peoples R China
5.Fucheng Tech Serv Ctr Family Planning, Fucheng 053700, Hebei, Peoples R China
6.Tianjin United Family Hosp, Reprod Med Ctr, Tianjin 300221, Peoples R China
7.Natl Res Inst Family Planning, Dept Male Clin Res, Natl Hlth & Family Planning Key Lab Male Reprod H, Beijing 100081, Peoples R China

Recommended Citation:
Tang, Wen-Hao,Zhuang, Xin-Jie,Shu, Ru-Ming,et al. The prevalence of erectile dysfunction among subjects with late-onset hypogonadism: a population-based study in China[J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,2015,8(8):13901-13910.
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