北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学药学院  > 期刊论文
学科主题: 药学
题名:
Additive-controlled stereoselective glycosylations of 2,3-oxazolidinone protected glucosamine or galactosamine thioglycoside donors with phenols based on preactivation protocol
作者: Qin, Qi; Xiong, De-Cai; Ye, Xin-Shan
关键词: Additive ; Stereoselectivity ; Glycosylation ; Preactivation ; Aryl glycoside
刊名: CARBOHYDRATE RESEARCH
发表日期: 2015-02-11
DOI: 10.1016/j.carres.2014.07.004
卷: 403, 页:104-114
收录类别: SCI ; IC
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Organic
研究领域[WOS]: Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]: NEIGHBORING GROUP PARTICIPATION ; HEPARIN-LIKE OLIGOSACCHARIDES ; ONE-POT SYNTHESIS ; BETA-MANNOPYRANOSIDES ; O-GLCNAC ; GLYCOCINNASPERIMICIN-D ; GLYCOSIDIC LINKAGES ; ALPHA-GLYCOSYLATION ; ENDOCYCLIC CLEAVAGE ; SULFOXIDE METHOD
英文摘要:

Stereo-controllable glycosylation reactions of 2,3-oxazolidinone protected glucosamine thioglycoside donor with different phenol acceptors based on preactivation protocol, are described. It was found that BF3.Et2O worked as alpha-directing additive, while TTBP acted as beta-directing additive. Simply by altering additives, either alpha-aryl glycosides or beta-aryl glycosides were achieved in a stereoselective manner. The additives were also applied to the stereoselective glycosylation reactions of 2,3-oxazolidinone protected galactosamine donor with phenol substrates. (C) 2014 Elsevier Ltd. All rights reserved.

语种: 英语
所属项目编号: 2012CB822100 ; 2013CB910700 ; 2012ZX09502001-001 ; 21232002 ; 2142015 ; YETP0063
项目资助者: Ministry of Science and Technology of China ; National Natural Science Foundation of China ; Beijing Natural Science Foundation ; Beijing Higher Education Young Elite Teacher Project
WOS记录号: WOS:000349085900013
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58410
Appears in Collections:北京大学药学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

Recommended Citation:
Qin, Qi,Xiong, De-Cai,Ye, Xin-Shan. Additive-controlled stereoselective glycosylations of 2,3-oxazolidinone protected glucosamine or galactosamine thioglycoside donors with phenols based on preactivation protocol[J]. CARBOHYDRATE RESEARCH,2015,403:104-114.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Qin, Qi]'s Articles
[Xiong, De-Cai]'s Articles
[Ye, Xin-Shan]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Qin, Qi]‘s Articles
[Xiong, De-Cai]‘s Articles
[Ye, Xin-Shan]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace