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学科主题: 临床医学
题名:
Repair of large full-thickness cartilage defect by activating endogenous peripheral blood stem cells and autologous periosteum flap transplantation combined with patellofemoral realignment
作者: Fu, Wei-Li1; Ao, Ying-Fang1; Ke, Xiao-Yan2,3; Zheng, Zhuo-Zhao4; Gong, Xi1; Jiang, Dong1; Yu, Jia-Kuo1
关键词: Mesenchymal stem cells ; Periosteum transplantation ; Patellofemoral realignment ; Cartilage defect
刊名: KNEE
发表日期: 2014-03-01
DOI: 10.1016/j.knee.2013.10.010
卷: 21, 期:2, 页:609-612
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Orthopedics ; Sport Sciences ; Surgery
研究领域[WOS]: Orthopedics ; Sport Sciences ; Surgery
关键词[WOS]: CHONDROCYTE IMPLANTATION ; FOLLOW-UP ; KNEE ; LESIONS
英文摘要:

Minimal-invasive procedure and one-step surgery offer autologous mesenchymal stem cells derived from peripheral blood (PB-MSCs) a promising prospective in the field of cartilage regeneration. We report a case of a 19-year-old male athlete of kickboxing with ICRS grade IV chondral lesions at the 60 degrees region of lateral femoral trochlea, which was repaired by activating endogenous PB-MSCs plus autologous periosteum flap transplantation combined with correcting the patellofemoral malalignment. After a 7.5 year follow-up, the result showed that the patient returned to competitive kickboxing. Second-look under arthroscopy showed a smooth surface at 8 months postoperation. The HOC 2000 subjective score, Lysholm score and Tegner score were 95, 98 and 9 respectively at the final follow up. CT and MRI evaluations showed a significant improvement compared with those of pre-operation. (C) 2013 Elsevier B.V. All rights reserved.

语种: 英语
WOS记录号: WOS:000335619500053
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58414
Appears in Collections:北京大学第三临床医学院_运动医学研究所_期刊论文

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作者单位: 1.Peking Univ, Inst Sports Med, Hosp 3, Beijing 100191, Peoples R China
2.Peking Univ, Dept Hematol, Hosp 3, Beijing 100191, Peoples R China
3.Peking Univ, Lymphoma Res Ctr, Hosp 3, Beijing 100191, Peoples R China
4.Peking Univ, Dept Diagnost Radiol, Hosp 3, Beijing 100191, Peoples R China

Recommended Citation:
Fu, Wei-Li,Ao, Ying-Fang,Ke, Xiao-Yan,et al. Repair of large full-thickness cartilage defect by activating endogenous peripheral blood stem cells and autologous periosteum flap transplantation combined with patellofemoral realignment[J]. KNEE,2014,21(2):609-612.
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