北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第二临床医学院  > 心血管内科  > 期刊论文
学科主题: 临床医学
题名:
A preliminary investigation of EZSCAN (TM) screening for impaired glucose tolerance and diabetes in a patient population
作者: Chen, Xiaolu1; Chen, Lizhu2,3; Ding, Rongjing4; Shi, Qiuting5; Zhang, Yuanyuan1; Hu, Dayi6
关键词: EZSCAN (TM) ; impaired glucose tolerance ; diabetes ; Chinese
刊名: EXPERIMENTAL AND THERAPEUTIC MEDICINE
发表日期: 2015-05-01
DOI: 10.3892/etm.2015.2358
卷: 9, 期:5, 页:1688-1694
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, Research & Experimental
研究领域[WOS]: Research & Experimental Medicine
关键词[WOS]: GLYCATED HEMOGLOBIN ; LIFE-STYLE ; MELLITUS ; CHINESE ; PREVENTION ; DIAGNOSIS ; CRITERIA ; TOOL
英文摘要:

EZSCAN (TM) is a non-invasive technology that evaluates sweat gland dysfunction using electrochemical skin conductance measurements, providing an opportunity to determine the risk of impaired glucose tolerance (IGT) and diabetes mellitus (DM). This study was conducted with the aims of detecting IGT and DM and investigating the efficacy and cut-off points of the EZSCAN test in a patient population. The traditional serum and plasma glucose tests were used as comparators. In this cross-sectional study, 270 previously undiagnosed patients (180 women and 90 men) with a high risk of glucose metabolism disorders (>= 45 years old) were enrolled. All patients underwent an oral glucose tolerance test (OGTT) and hemoglobin A1c (HbA1c), fasting plasma glucose (FPG) and EZSCAN tests. Forty (14.8%) patients had newly diagnosed DM (NDM), 79 (29.3%) had IGT and 151 (55.9%) had normal glucose tolerance. The EZSCAN values of these groups were 48 +/- 11, 47 +/- 11 and 34 +/- 13%, respectively. For all patients, the correlation coefficient of EZSCAN was 0.462 with the OGTT (P<0.001), 0.182 with the FPG test (P<0.001) and 0.379 with the HbA lc test (P<0.001). The EZSCAN cut-off point for the detection of IGT was 37% [sensitivity, 82%; specificity, 62%; area under the curve (AUC), 0.778], and the cut-off point for NDM was 50% (sensitivity, 53%; specificity, 59%; AUC, 0.528). This study demonstrated that the non-invasive EZSCAN system is an effective screening tool for the detection of glucose dysfunction in the population tested, and that its performance in detecting previously undiagnosed IGT is superior to its performance in detecting DM.

语种: 英语
WOS记录号: WOS:000353849700021
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58426
Appears in Collections:北京大学第二临床医学院_心血管内科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Sichuan Prov Peoples Hosp, Chengdu 610072, Sichuan, Peoples R China
2.Peking Univ, Peoples Hosp, Dept Cardiol, Beijing 100044, Peoples R China
3.Chongqing Int Sci & Technol Cooperat Ctr Child De, Key Lab Pediat Chongqing, Key Lab Child Dev & Disorders, Minist Educ, Chongqing 400016, Sichuan, Peoples R China
4.Sichuan Acad Med Sci, Dept Cardiol, Chengdu 610072, Sichuan, Peoples R China
5.Xianghe Community Hosp, Dept Internal Med, Xianghe 065400, Hebei, Peoples R China
6.Chongqing Med Univ, Affiliated Hosp 1, Dept Cardiol, Chongqing 400016, Sichuan, Peoples R China

Recommended Citation:
Chen, Xiaolu,Chen, Lizhu,Ding, Rongjing,et al. A preliminary investigation of EZSCAN (TM) screening for impaired glucose tolerance and diabetes in a patient population[J]. EXPERIMENTAL AND THERAPEUTIC MEDICINE,2015,9(5):1688-1694.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Chen, Xiaolu]'s Articles
[Chen, Lizhu]'s Articles
[Ding, Rongjing]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Chen, Xiaolu]‘s Articles
[Chen, Lizhu]‘s Articles
[Ding, Rongjing]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace