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学科主题临床医学
Establishment of a database of fetal congenital heart malformations and preliminary investigation of its clinical application
Gao, Jun-Xue; Pei, Qiu-Yan; Li, Yun-tao; Yang, Zhen-Juan
关键词anatomic section congenital heart disease database fetal
刊名TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY
2015-06-01
DOI10.1016/j.tjog.2015.01.002
54期:3页:284-289
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Obstetrics & Gynecology
研究领域[WOS]Obstetrics & Gynecology
关键词[WOS]DISEASE ; DIAGNOSES
英文摘要

Objective: The aim of this study was to create a database of anatomical ultrathin cross-sectional images of fetal hearts with different congenital heart diseases (CHDs) and preliminarily to investigate its clinical application.

Materials and methods: Forty Chinese fetal heart samples from induced labor due to different CHDs were cut transversely at 60-mu m thickness. All thoracic organs were removed from the thoracic cavity after formalin fixation, embedded in optimum cutting temperature compound, and then frozen at -25 degrees C for 2 hours. Subsequently, macro shots of the frozen serial sections were obtained using a digital camera in order to build a database of anatomical ultrathin cross-sectional images.

Results: Images in the database clearly displayed the fetal heart structures. After importing the images into three-dimensional software, the following functions could be realized: (1) based on the original database of transverse sections, databases of sagittal and coronal sections could be constructed; and (2) the original and constructed databases could be displayed continuously and dynamically, and rotated in arbitrary angles. They could also be displayed synchronically. The aforementioned functions of the database allowed for the retrieval of images and three-dimensional anatomy characteristics of the different fetal CHDs, and virtualization of fetal echocardiography findings.

Conclusion: A database of 40 different cross-sectional fetal CHDs was established. An extensive database library of fetal CHDs, from which sonographers and students can study the anatomical features of fetal CHDs and virtualize fetal echocardiography findings via either centralized training or distance education, can be established in the future by accumulating further cases. Copyright (C) 2015, Taiwan Association of Obstetrics & Gynecology. Published by Elsevier Taiwan LLC. All rights reserved.

语种英语
WOS记录号WOS:000359030000015
项目编号2011-4022-07
资助机构Capital Project of Fund Development
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/58449
专题北京大学第二临床医学院_超声影像科
北京大学第二临床医学院_妇科
作者单位Peking Univ, Peoples Hosp, Dept Ultrasound, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Gao, Jun-Xue,Pei, Qiu-Yan,Li, Yun-tao,et al. Establishment of a database of fetal congenital heart malformations and preliminary investigation of its clinical application[J]. TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY,2015,54(3):284-289.
APA Gao, Jun-Xue,Pei, Qiu-Yan,Li, Yun-tao,&Yang, Zhen-Juan.(2015).Establishment of a database of fetal congenital heart malformations and preliminary investigation of its clinical application.TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY,54(3),284-289.
MLA Gao, Jun-Xue,et al."Establishment of a database of fetal congenital heart malformations and preliminary investigation of its clinical application".TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY 54.3(2015):284-289.
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