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学科主题临床医学
The role of nuclear matrix protein 22 combined with bladder tumor antigen stat test in surveillance of recurring bladder cancer
Xu, KX; Tam, PC; Hou, SK; Wang, XF; Bai, WJ
关键词nuclear matrix protein 22 bladder tumor antigen bladder cancer
刊名CHINESE MEDICAL JOURNAL
2002-11-01
115期:11页:1736-1738
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
研究领域[WOS]General & Internal Medicine
关键词[WOS]TRANSITIONAL-CELL CARCINOMA ; COST-EFFECTIVE TEST ; BTA STAT ; NMP22 ; SPECIFICITY ; CYTOLOGY ; MARKER ; RISK
英文摘要

Objective To investigate a non-invasive, effective and rapid mode of detecting the recurrence of bladder cancer during follow-up.

Methods Ninety patients following transurethral resection of bladder tumor (TURBt) surgery were recruited from January 1998 to March 2000. Standard ELISA was used to determine the quantity of nuclear matrix protein (NMP-22) in urine of all bladder cancer patients during their follow-up periods. Urine bladder tumor antigen (BTA) stat test was simultaneously performed and followed by cystoscopy.

Results The total positive rates of urinary NMP-22 and BTA stat test were 76.7% (33/43) and 67.4% (29/43), respectively. Comparatively, this positive rate would increase to 93.0% (40/43) when the combination of both urine NMP-22 and BTA test were adopted.

Conclusion Examination of NMP-22 in urine is a rapid and effective way to detect the recurrence of bladder cancer. It combined with BTA test, NMP-22 may be used as a non-invasive method in surveillance of recurring of bladder cancer, which may reduce the frequency of patients needing to undergo conventional invasive cystoscopy.

语种英语
WOS记录号WOS:000179926400029
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/58455
专题北京大学第二临床医学院_泌尿外科
作者单位1.Peking Univ, Peoples Hosp, Dept Urol, Beijing 100044, Peoples R China
2.Univ Hong Kong, Queen Mary Hosp, Dept Surg, Hong Kong, Hong Kong, Peoples R China
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Xu, KX,Tam, PC,Hou, SK,et al. The role of nuclear matrix protein 22 combined with bladder tumor antigen stat test in surveillance of recurring bladder cancer[J]. CHINESE MEDICAL JOURNAL,2002,115(11):1736-1738.
APA Xu, KX,Tam, PC,Hou, SK,Wang, XF,&Bai, WJ.(2002).The role of nuclear matrix protein 22 combined with bladder tumor antigen stat test in surveillance of recurring bladder cancer.CHINESE MEDICAL JOURNAL,115(11),1736-1738.
MLA Xu, KX,et al."The role of nuclear matrix protein 22 combined with bladder tumor antigen stat test in surveillance of recurring bladder cancer".CHINESE MEDICAL JOURNAL 115.11(2002):1736-1738.
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