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学科主题: 临床医学
题名:
Predictors of Diabetes in Older People in Urban China
作者: Chen, Ruoling1,4; Song, Yiqing2; Hu, Zhi1; Brunner, Eric John3
刊名: PLOS ONE
发表日期: 2012-11-30
DOI: 10.1371/journal.pone.0050957
卷: 7, 期:11
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Multidisciplinary Sciences
研究领域[WOS]: Science & Technology - Other Topics
关键词[WOS]: GMS-AGECAT PREVALENCE ; RISK-FACTORS ; MRC-ALPHA ; DEPRESSION ; HEALTH ; COMMUNITY ; MELLITUS ; WOMEN ; MEN ; POPULATION
英文摘要:

Background: China has the largest number of people with diabetes in the world. Over the last 30 years China has experienced rapid economic growth and a growing income gap between rich and poor. The population is ageing, however diabetes in older people has not been well studied to date. In this study we determined incidence and predictors of diabetes in older Chinese people.

Methods: During 2001, using a standard interview method, we examined 1,317 adults aged >= 65 years who did not have diabetes in the city of Hefei, and characterized baseline risk factors. Over 7.5 years of follow up, we documented incident diabetes using self-reported doctor diagnosis and the cause of death in the whole cohort, and HbA(1C) >= 48 mmol/mol in a nested case-control sample. A multivariate Cox regression model was employed to investigate risk of diabetes in relation to baseline risk factors.

Results: During follow up, 119 persons had newly diagnosed diabetes. World age-standardised incidence of diabetes was 24.5 (95% CI 19.5-29.5) per 1,000 person-years. Risk of diabetes was significantly and positively associated with income, waist circumference and body mass index, smoking and uncontrolled hypertension, but negatively associated with having a hobby of walking and frequency of visiting children/other relatives and contacting neighbours/friends. Higher income was significantly associated with increased diabetes risk regardless of cardiovascular and psychosocial risk factors. Compared to those with middle income and no psychosocial risk factors, the hazard ratio for incident diabetes among participants with high income and psychosocial risk was 2.13 (95% CI 1.02-4.45).

Conclusions: Increasing incidence of diabetes in relation to high income has become an important public health issue in China. Maintaining social networks and gentle physical activities and reducing psychosocial factors may be integrated into current multi-faceted preventive strategies for curbing the epidemic of diabetes in the older population.

语种: 英语
所属项目编号: 45NOV06 ; TBF-M09-50
项目资助者: BUPA Foundation, UK ; British Heart Foundation
WOS记录号: WOS:000312376100243
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58478
Appears in Collections:北京大学第三临床医学院_心血管内科_期刊论文

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作者单位: 1.Anhui Med Univ, Sch Hlth Adm, Hefei, Anhui, Peoples R China
2.Peking Univ, Hosp 3, Inst Vasc Med, Beijing 100871, Peoples R China
3.UCL, Sch Med, Dept Epidemiol & Publ Hlth, London W1N 8AA, England
4.Kings Coll London, Sch Med, Dept Primary Care & Publ Hlth Sci, London, England

Recommended Citation:
Chen, Ruoling,Song, Yiqing,Hu, Zhi,et al. Predictors of Diabetes in Older People in Urban China[J]. PLOS ONE,2012,7(11).
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