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学科主题: 临床医学
题名:
Cluster Phenomenon of Vertebral Refractures After Percutaneous Vertebroplasty in a Patient With Glucocorticosteroid-Induced Osteoporosis Case Report and Review of the Literature
作者: Sun, Haolin1; Sharma, Shallu2; Li, Chunde1
关键词: vertebral compression fracture ; vertebroplasty ; osteoporosis ; steroids
刊名: SPINE
发表日期: 2013-12-01
DOI: 10.1097/BRS.0b013e3182a8c488
卷: 38, 期:25, 页:E1628-E1632
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Orthopedics
研究领域[WOS]: Neurosciences & Neurology ; Orthopedics
关键词[WOS]: STEROID-INDUCED OSTEOPOROSIS ; COMPRESSION FRACTURES ; RANDOMIZED-TRIAL ; KYPHOPLASTY
英文摘要:

Study Design. A case report and literature review.

Objective. To describe a rare cluster phenomenon of spontaneous vertebral refractures in a patient with glucocorticosteroid-induced osteoporosis (GIOP) subsequent to percutaneous vertebroplasty (PVP) for the management of initial vertebral compression fractures (VCFs).

Summary of Background Data. PVP has become the popular strategy for stabilizing osteoporotic VCFs and obtaining rapid pain alleviation and earlier restoration of mobility in both patients with primary osteoporosis and patients with glucocorticosteroid-induced osteoporosis. However, current data are insufficient to recommend routine use of PVP for VCFs caused by GIOP as recent retrospective studies indicate that the risk of vertebral refractures is much higher in patients with GIOP than those with primary osteoporosis.

Methods. We reported a 63-year-old Chinese female with GIOP as well as pulmonary infection who underwent PVP for the management of initial VCFs, experienced the cluster phenomenon of spontaneous vertebral refractures.

Results. Within a 4-month period, she underwent a total of 6 PVP operations with 13 cement-augmented vertebral bodies from T5-L5. Eleven refractures after the initial PVP procedures included 3 remote-level fractures, 4 adjacent-level fractures, 1 pincher body fracture, and 3 fractures in previously augmented bodies. The average interval between each PVP operation was 23.6 days.

Conclusion. The use of PVP as a therapeutic alternative for the treatment of VCFs in patients with GIOP is still controversial. As seen in our case, even when the management decisions were made in consideration of the patient′s pulmonary infection, the outcome was disastrous with the cluster phenomenon of vertebral refractures. Current findings suggest a compelling need for high-quality studies investigating cement augmentation procedures in patients with VCF with GIOP.

语种: 英语
WOS记录号: WOS:000330381500009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58494
Appears in Collections:北京大学第一临床医学院_骨科_期刊论文

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作者单位: 1.Aarhus Univ Hosp, Dept Orthoped E, DK-8000 Aarhus, Denmark
2.Peking Univ, Hosp 1, Dept Orthoped Surg, Beijing 100034, Peoples R China

Recommended Citation:
Sun, Haolin,Sharma, Shallu,Li, Chunde. Cluster Phenomenon of Vertebral Refractures After Percutaneous Vertebroplasty in a Patient With Glucocorticosteroid-Induced Osteoporosis Case Report and Review of the Literature[J]. SPINE,2013,38(25):E1628-E1632.
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