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Cluster Phenomenon of Vertebral Refractures After Percutaneous Vertebroplasty in a Patient With Glucocorticosteroid-Induced Osteoporosis Case Report and Review of the Literature
Sun, Haolin1; Sharma, Shallu2; Li, Chunde1
关键词vertebral compression fracture vertebroplasty osteoporosis steroids
刊名SPINE
2013-12-01
DOI10.1097/BRS.0b013e3182a8c488
38期:25页:E1628-E1632
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Clinical Neurology ; Orthopedics
研究领域[WOS]Neurosciences & Neurology ; Orthopedics
关键词[WOS]STEROID-INDUCED OSTEOPOROSIS ; COMPRESSION FRACTURES ; RANDOMIZED-TRIAL ; KYPHOPLASTY
英文摘要

Study Design. A case report and literature review.

Objective. To describe a rare cluster phenomenon of spontaneous vertebral refractures in a patient with glucocorticosteroid-induced osteoporosis (GIOP) subsequent to percutaneous vertebroplasty (PVP) for the management of initial vertebral compression fractures (VCFs).

Summary of Background Data. PVP has become the popular strategy for stabilizing osteoporotic VCFs and obtaining rapid pain alleviation and earlier restoration of mobility in both patients with primary osteoporosis and patients with glucocorticosteroid-induced osteoporosis. However, current data are insufficient to recommend routine use of PVP for VCFs caused by GIOP as recent retrospective studies indicate that the risk of vertebral refractures is much higher in patients with GIOP than those with primary osteoporosis.

Methods. We reported a 63-year-old Chinese female with GIOP as well as pulmonary infection who underwent PVP for the management of initial VCFs, experienced the cluster phenomenon of spontaneous vertebral refractures.

Results. Within a 4-month period, she underwent a total of 6 PVP operations with 13 cement-augmented vertebral bodies from T5-L5. Eleven refractures after the initial PVP procedures included 3 remote-level fractures, 4 adjacent-level fractures, 1 pincher body fracture, and 3 fractures in previously augmented bodies. The average interval between each PVP operation was 23.6 days.

Conclusion. The use of PVP as a therapeutic alternative for the treatment of VCFs in patients with GIOP is still controversial. As seen in our case, even when the management decisions were made in consideration of the patient′s pulmonary infection, the outcome was disastrous with the cluster phenomenon of vertebral refractures. Current findings suggest a compelling need for high-quality studies investigating cement augmentation procedures in patients with VCF with GIOP.

语种英语
WOS记录号WOS:000330381500009
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/58494
专题北京大学第一临床医学院_骨科
作者单位1.Aarhus Univ Hosp, Dept Orthoped E, DK-8000 Aarhus, Denmark
2.Peking Univ, Hosp 1, Dept Orthoped Surg, Beijing 100034, Peoples R China
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Sun, Haolin,Sharma, Shallu,Li, Chunde. Cluster Phenomenon of Vertebral Refractures After Percutaneous Vertebroplasty in a Patient With Glucocorticosteroid-Induced Osteoporosis Case Report and Review of the Literature[J]. SPINE,2013,38(25):E1628-E1632.
APA Sun, Haolin,Sharma, Shallu,&Li, Chunde.(2013).Cluster Phenomenon of Vertebral Refractures After Percutaneous Vertebroplasty in a Patient With Glucocorticosteroid-Induced Osteoporosis Case Report and Review of the Literature.SPINE,38(25),E1628-E1632.
MLA Sun, Haolin,et al."Cluster Phenomenon of Vertebral Refractures After Percutaneous Vertebroplasty in a Patient With Glucocorticosteroid-Induced Osteoporosis Case Report and Review of the Literature".SPINE 38.25(2013):E1628-E1632.
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