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学科主题基础医学
Using laser confocal scanning microscope to study ischemia-hypoxia injury in rat brain slice
Wang, XY; Xing, H; He, QH; Xu, JL; Wu, BJ
关键词laser confocal scanning microscope brain ischemia-hypoxia injury lipid peroxide 2, 7-dichlorofluorescin diacetate
刊名CHINESE SCIENCE BULLETIN
2000
45期:1页:49-51
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Multidisciplinary Sciences
研究领域[WOS]Science & Technology - Other Topics
关键词[WOS]CENTRAL-NERVOUS-SYSTEM
英文摘要

The level of lipid peroxidation and cellular necrosis in rat living brain slices during brain ischemia-hypoxia injury have been observed using a laser confocal scanning microscope (LCSM) with double labeling of fluorescent probes D-399 (2, 7-dichlorofluorescin diacetate) and propidium iodide (PI). The hypoxia and/or reoxygenation injury in rat brain slices is markedly decreased by pretreatment with L-NG-nitro-arginine (L-NNA) and N-acetylcysteine (NAC), showing that the nitric oxide (NO) and other free radicals play an important role in brain ischemia-hypoxia injury.

语种英语
WOS记录号WOS:000084526400010
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/58536
专题基础医学院_生物物理学系
作者单位1.Beijing Med Univ, Dept Biophys, Beijing 100083, Peoples R China
2.Beijing Med Univ, Analyt Ctr Medicopharm, Beijing 100083, Peoples R China
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GB/T 7714
Wang, XY,Xing, H,He, QH,et al. Using laser confocal scanning microscope to study ischemia-hypoxia injury in rat brain slice[J]. CHINESE SCIENCE BULLETIN,2000,45(1):49-51.
APA Wang, XY,Xing, H,He, QH,Xu, JL,&Wu, BJ.(2000).Using laser confocal scanning microscope to study ischemia-hypoxia injury in rat brain slice.CHINESE SCIENCE BULLETIN,45(1),49-51.
MLA Wang, XY,et al."Using laser confocal scanning microscope to study ischemia-hypoxia injury in rat brain slice".CHINESE SCIENCE BULLETIN 45.1(2000):49-51.
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