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学科主题: 公共卫生
题名:
Effect of oat intake on glycaemic control and insulin sensitivity: a meta-analysis of randomised controlled trials
作者: Bao, Lei; Cai, Xiaxia; Xu, Meihong; Li, Yong
关键词: Oats ; beta-Glucan ; Glycaemic control ; Meta-analyses ; Type 2 diabetes mellitus
刊名: BRITISH JOURNAL OF NUTRITION
发表日期: 2014-08-14
DOI: 10.1017/S0007114514000889
卷: 112, 期:3, 页:457-466
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Nutrition & Dietetics
研究领域[WOS]: Nutrition & Dietetics
关键词[WOS]: HEALTHGRAIN DIVERSITY SCREEN ; BETA-GLUCAN ; POSTPRANDIAL GLUCOSE ; OXIDATIVE STRESS ; PLASMA-GLUCOSE ; SERUM-LIPIDS ; CARDIOVASCULAR-DISEASE ; DIABETES PREVENTION ; FIBER COMPONENTS ; LOWERS GLUCOSE
英文摘要:

The present meta-analysis of randomised controlled trials (RCT) aimed to investigate the effect of oat intake on glycaemic control and insulin sensitivity. A literature search was carried out in PubMed, ScienceDirect Online and The Cochrane Library (up to October 2013) for RCT that assessed the effect of oat intake on glucose control and insulin sensitivity. A total of fifteen articles with 673 subjects met the inclusion criteria. A random-effects model was used when the overall pooled studies exhibited significant heterogeneity. Otherwise, a fixed-effects model was used. Compared with controls, oat intake significantly reduced the concentrations of fasting insulin by 26 29 (95% CI - 12.32, -0.27) pmol/l (P=0.04) and the values of glucose AUC (GAUC; 0-120 min) by -30.23 (95% CI -43.65, -16.81) min X mmol/l (P<0.0001). There was a slight decrease in fasting glucose concentrations, glycated Hb concentrations and homeostatic model assessment-insulin resistance values in subjects who consumed oats, but the difference was not significant. In conclusion, oat intake significantly lowers fasting insulin concentrations and GAUC values. To further investigate the effect of oat intake on fasting glucose concentrations, additional long-term and high-quality RCT with a parallel design are required.

语种: 英语
WOS记录号: WOS:000339054100018
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58541
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: Peking Univ, Sch Publ Hlth, Dept Nutr & Food Hyg, Beijing 100191, Peoples R China

Recommended Citation:
Bao, Lei,Cai, Xiaxia,Xu, Meihong,et al. Effect of oat intake on glycaemic control and insulin sensitivity: a meta-analysis of randomised controlled trials[J]. BRITISH JOURNAL OF NUTRITION,2014,112(3):457-466.
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