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学科主题: 基础医学
题名:
Clinical outcome of incidental pelvic node malignant B-cell lymphomas discovered at the time of radical prostatectomy
作者: He, Huiying; Cheng, Liang; Weiss, Lawrence M.; Chu, Peiguo G.
关键词: pelvic lymph node ; B-cell lymphoma ; prognosis
刊名: LEUKEMIA & LYMPHOMA
发表日期: 2007
DOI: 10.1080/10428190701584007
卷: 48, 期:10, 页:1976-1980
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology ; Hematology
研究领域[WOS]: Oncology ; Hematology
关键词[WOS]: SMALL LYMPHOCYTIC LYMPHOMA ; NON-HODGKINS-LYMPHOMA ; CANCER
英文摘要:

Incidental pelvic node malignant B-cell lymphomas diagnosed at the time of radical prostatectomy are rare. Their clinical outcome has not been studied. We studied thirteen such cases with long-term clinical follow-up. Patients were followed between 9 and 94 months after surgery. Of 13 cases, 9 were chronic lymphocytic leukemia/small lymphocytic lymphoma ( CLL/SLL), 3 marginal zone B-cell lymphoma ( MZL) and 1 mantle cell lymphoma ( MCL). All 13 patients did not receive radiation or chemotherapy; and five of 13 cases showed hematologic evidence of lymphoma progression between 1 and 5 months after radical prostatectomy. After progression, the mantle cell lymphoma patient received aggressive chemotherapy and had systemic dissemination. Two of 13 cases had recurrent prostate carcinoma. None of 13 patients had died from lymphoma or prostate carcinoma at the last follow-up. In conclusion, most incidental pelvic node lymphomas ( 8/13) showed no evidence of systemic dissemination to peripheral blood or bone marrow after a mean 42.8 weeks of follow-up despite the fact that no additional treatment was given. Strong consideration should be given to withholding further treatment in patients diagnosed with pelvic low-grade B-cell lymphoma at the time of radical prostatectomy until disease progression occurs.

语种: 英语
WOS记录号: WOS:000249872600015
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58680
Appears in Collections:基础医学院_病理学系_期刊论文

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作者单位: 1.City Hope Natl Med Ctr, Dept Pathol, Div Pathol, Duarte, CA 91010 USA
2.Beijing Univ, Hlth Sci Ctr, Dept Pathol, Beijing 100871, Peoples R China
3.Indiana Univ, Sch Med, Dept Pathol, Indianapolis, IN 46202 USA

Recommended Citation:
He, Huiying,Cheng, Liang,Weiss, Lawrence M.,et al. Clinical outcome of incidental pelvic node malignant B-cell lymphomas discovered at the time of radical prostatectomy[J]. LEUKEMIA & LYMPHOMA,2007,48(10):1976-1980.
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