|Screening for bipolar disorder with the Mood Disorders Questionnaire in patients diagnosed as major depressive disorder - The experience in China|
|Hu, Chen2; Xiang, Yu-Tao1; Wang, Gang2; Ungvari, Gabor S.3; Dickerson, Faith B.4; Kilbourne, Amy M.5,6; Lai, Kelly Y. C.1; Si, Tian-Mei7; Fang, Yi-Ru8; Lu, Zheng9; Yang, Hai-Chen10; Hu, Jian11; Chen, Zhi-Yu12; Huang, Yi13; Sun, Jing14; Wang, Xiao-Ping15; Li, Hui-Chun16; Zhang, Jin-Bei17; Chiu, Helen F. K.1|
|关键词||Bipolar disorder Major depressive disorder Screening Diagnostic criteria|
|刊名||JOURNAL OF AFFECTIVE DISORDERS|
|收录类别||SCI ; SSCI|
|WOS标题词||Science & Technology|
|类目[WOS]||Clinical Neurology ; Psychiatry|
|研究领域[WOS]||Neurosciences & Neurology ; Psychiatry|
|关键词[WOS]||INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW ; SPECTRUM DISORDER ; DSM-IV ; VALIDATION ; VERSION ; INSTRUMENT ; UNIPOLAR ; LIFETIME ; MINI ; MDQ|
Background: Bipolar disorder (BD) is often misdiagnosed as a major depressive disorder (MDD). This study aimed to test the usefulness of the screening tool, the Mood Disorders Questionnaire (MDQ), to identify BD patients misdiagnosed as MDD in Chinese clinical settings.
Methods: A total of 1487 patients treated for MDD were consecutively examined in 13 mental health centers in China. The patients′ socio-demographic and clinical characteristics were recorded using a standardized protocol and data collection procedure. The MDQ was completed by patients to identify symptoms characteristic of BD. DSM-IV diagnoses were established using the Mini International Neuropsychiatric Interview (MINI).
Results: Three hundred-nine of the 1487 patients (20.8%) satisfied DSM-IV criteria for BD; 118 (7.9%) for BD-I and 191 (12.8%) for BD-II on the MINI. The optimal cut-off point on the MDQ to differentiate BD from MDD was 3, while cut-off points of 5 and 3 differentiated BD-I and BD-II from MDD, respectively. The maximum sensitivity was 0.31, 0.45 and 0.22 for differentiating BD. BD-I and BD-II from MDD, respectively.
Conclusions: The optimal cutoff points of the MDQ for screening BD in Chinese patients originally diagnosed as MDD were considerably lower than those in earlier studies. The routine clinical use of the MDQ as a screening scale for BD in Chinese patients treated for MDD does not seem to be justified. (c) 2012 Elsevier B.V. All rights reserved.
|作者单位||1.Sheppard Pratt, Stanley Res Program, Baltimore, MD USA|
2.Vet Adm Ann Arbor Ctr Clin Management Res, Ann Arbor, MI USA
3.Chinese Univ Hong Kong, Dept Psychiat, Tai Po, Hong Kong, Peoples R China
4.Capital Med Univ, Beijing Anding Hosp, Mood Disorders Ctr, Beijing, Peoples R China
5.Univ Western Australia, Dept Psychiat &Clin Neurosci, Perth, WA 6009, Australia
6.Univ Michigan, Sch Med, Dept Psychiat, Ann Arbor, MI USA
7.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
8.Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Div Mood Disorders, Shanghai 200030, Peoples R China
9.Tongji Univ, Sch Med, Shanghai Tongji Hosp, Shanghai 200092, Peoples R China
10.Shenzhen Mental Hlth Ctr, Div Mood Disorders, Shenzhen, Guangdong, Peoples R China
11.Harbin Med Univ, Hosp 1, Harbin, Heilongjiang Pr, Peoples R China
12.Hangzhou Seventh Peoples Hosp, Hangzhou, Zhejiang, Peoples R China
13.Sichuan Univ, W China Hosp, Chengdu, Sichuan Provinc, Peoples R China
14.Nanjing Med Univ, Affiliated Brain Hosp, Nanjing, Jiangsu, Peoples R China
15.Cent S Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha, Hunan, Peoples R China
16.Zhejiang Univ, Coll Med, Affiliated Hosp 2, Hangzhou, Zhejiang, Peoples R China
17.Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou, Guangdong, Peoples R China
|Hu, Chen,Xiang, Yu-Tao,Wang, Gang,et al. Screening for bipolar disorder with the Mood Disorders Questionnaire in patients diagnosed as major depressive disorder - The experience in China[J]. JOURNAL OF AFFECTIVE DISORDERS,2012,141(1):40-46.|
|APA||Hu, Chen.,Xiang, Yu-Tao.,Wang, Gang.,Ungvari, Gabor S..,Dickerson, Faith B..,...&Chiu, Helen F. K..(2012).Screening for bipolar disorder with the Mood Disorders Questionnaire in patients diagnosed as major depressive disorder - The experience in China.JOURNAL OF AFFECTIVE DISORDERS,141(1),40-46.|
|MLA||Hu, Chen,et al."Screening for bipolar disorder with the Mood Disorders Questionnaire in patients diagnosed as major depressive disorder - The experience in China".JOURNAL OF AFFECTIVE DISORDERS 141.1(2012):40-46.|