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学科主题: 临床医学
题名:
Treatment of in-stent coronary restenosis with excimer laser angioplasty
作者: Liu, ML; Chow, WH; Kwok, OH; Jim, MH; Yip, A; Fan, K; Chan, E
关键词: excimer laser coronary angioplasty ; in-stent restenosis ; PTCA
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2000
卷: 113, 期:1, 页:14-17
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: INTRAVASCULAR ULTRASOUND ; MECHANISMS
英文摘要:

Objective To evaluate the efficacy and safety of excimer laser coronary angioplasty (ELCA) with adjunctive balloon angioplasty in patient with in-stent restenosis.

Methods ELCA was performed in 20 patients of in-stent restenosis. All patients were symptomatic and had class III - IV angina. ELCA was performed with the Spectranetics CVX-300 System. The laser catheter of Vittesse C (concentric) and E (eccentric) with diameter of 1.4-2.0 mm was used.

Results Laser catheter crossed all stenotic stents without difficulty. The lesion length was 4.6 - 51.2 mm, mean 20.7 +/- 13.7 mm, including 14 lesions > 10 mm. Laser treatment alone increased minimal lumen diameter (MLD) from 0.3 +/- 0.3 mm to 1.4 +/- 0.3 mm ( P < 0.0001) and improved the diameter stenosis from 88.8% +/- 10.0% to 46.0% +/- 8.0% (P < 0.0001). Adjunctive balloon angioplasty further increased minimal lumen diameter to 2.3 +/- 0.7 mm and reduced diameter stenosis to 14.2% +/- 8.2% (P < 0.0001). At follow-up (1 - 17 months, mean 8.9 +/- 5.7 months), 17 (85%) patients had remained asymptomatic, 3 (15%) patients had mild to moderate exertional angina, 1 (5%) patient received CABG.

Conclusion ELCA with adjunctive percutaneous transluminal coronary angioplasty (PTCA) is an efficient and safe technique to debulk tissue in the patient with in-stent restenosis. The incidence of procedural related complication was low and ELCA may be used as a good method for in-stent restenosis treatment.

语种: 英语
WOS记录号: WOS:000087114600004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58719
Appears in Collections:北京大学第一临床医学院_心血管内科_期刊论文

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作者单位: 1.Grantham Hosp, Hong Kong, Hong Kong, Peoples R China
2.Beijing Med Univ, Teaching Hosp 1, Dept Cardiol, Beijing 100034, Peoples R China

Recommended Citation:
Liu, ML,Chow, WH,Kwok, OH,et al. Treatment of in-stent coronary restenosis with excimer laser angioplasty[J]. CHINESE MEDICAL JOURNAL,2000,113(1):14-17.
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