|Plasma fibrinogen: A possible link between job stress and cardiovascular disease among Chinese workers|
|Xu, Weixian1,2; Hang, Juan1,2,3; Guo, Lijun1,2; Zhao, Yiming4; Li, Zhaoping1,2; Gao, Wei1,2|
|关键词||effort-reward imbalance job stress fibrinogen cardiovascular disease|
|刊名||AMERICAN JOURNAL OF INDUSTRIAL MEDICINE|
|WOS标题词||Science & Technology|
|类目[WOS]||Public, Environmental & Occupational Health|
|研究领域[WOS]||Public, Environmental & Occupational Health|
|关键词[WOS]||EFFORT-REWARD IMBALANCE ; CORONARY-HEART-DISEASE ; PSYCHOSOCIAL FACTORS ; JAPANESE MALE ; RISK-FACTORS ; STRAIN ; INFLAMMATION ; POPULATION ; HEALTH ; ASSOCIATION|
Background Little is known about the effect of effortreward imbalance (ERI) on fibrinogen. We aimed to examine the association between ERI and fibrinogen among Chinese workers.
Methods A total of 732 subjects without vascular diseases were analyzed. Associations between job stress evaluated by ERI model and plasma fibrinogen were explored by multiple regression.
Results Effort, overcommitment, and ERI were significantly positively associated with fibrinogen, while reward was negatively related with fibrinogen both for men and for women. Compared with low level group, high level of effort, overcommitment, and ERI significantly increased risk of elevated fibrinogen (more than mean concentration) with adjusted OR of 3.3, 12.5, and 7.7 for men; 2.9, 7.2, and 7.2 for women, respectively; however, high reward reduced 80% risk for elevated fibrinogen.
Conclusions Effort, overcommitment, and ERI are significantly associated with fibrinogen among Chinese workers. High fibrinogen may be a possible link between job stress and cardiovascular disease. Am. J. Ind. Med. 55: 167-175, 2012. (C) 2011 Wiley Periodicals, Inc.
|资助机构||Major National Basic Research Program of the PR China|
|作者单位||1.Peking Univ Shenzhen Hosp, Dept Geriatr, Shenzhen, Peoples R China|
2.Minist Educ, Key Lab Mol Cardiovasc Sci, Beijing, Peoples R China
3.Peking Univ Third Hosp, Dept Cardiol, Beijing 100191, Peoples R China
4.Peking Univ Third Hosp, Res Ctr Occupat Med, Beijing 100191, Peoples R China
|Xu, Weixian,Hang, Juan,Guo, Lijun,et al. Plasma fibrinogen: A possible link between job stress and cardiovascular disease among Chinese workers[J]. AMERICAN JOURNAL OF INDUSTRIAL MEDICINE,2012,55(2):167-175.|
|APA||Xu, Weixian,Hang, Juan,Guo, Lijun,Zhao, Yiming,Li, Zhaoping,&Gao, Wei.(2012).Plasma fibrinogen: A possible link between job stress and cardiovascular disease among Chinese workers.AMERICAN JOURNAL OF INDUSTRIAL MEDICINE,55(2),167-175.|
|MLA||Xu, Weixian,et al."Plasma fibrinogen: A possible link between job stress and cardiovascular disease among Chinese workers".AMERICAN JOURNAL OF INDUSTRIAL MEDICINE 55.2(2012):167-175.|