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学科主题: 临床医学
题名:
Plasma fibrinogen: A possible link between job stress and cardiovascular disease among Chinese workers
作者: Xu, Weixian1,2; Hang, Juan1,2,3; Guo, Lijun1,2; Zhao, Yiming4; Li, Zhaoping1,2; Gao, Wei1,2
关键词: effort-reward imbalance ; job stress ; fibrinogen ; cardiovascular disease
刊名: AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
发表日期: 2012-02-01
DOI: 10.1002/ajim.21017
卷: 55, 期:2, 页:167-175
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Public, Environmental & Occupational Health
研究领域[WOS]: Public, Environmental & Occupational Health
关键词[WOS]: EFFORT-REWARD IMBALANCE ; CORONARY-HEART-DISEASE ; PSYCHOSOCIAL FACTORS ; JAPANESE MALE ; RISK-FACTORS ; STRAIN ; INFLAMMATION ; POPULATION ; HEALTH ; ASSOCIATION
英文摘要:

Background Little is known about the effect of effortreward imbalance (ERI) on fibrinogen. We aimed to examine the association between ERI and fibrinogen among Chinese workers.

Methods A total of 732 subjects without vascular diseases were analyzed. Associations between job stress evaluated by ERI model and plasma fibrinogen were explored by multiple regression.

Results Effort, overcommitment, and ERI were significantly positively associated with fibrinogen, while reward was negatively related with fibrinogen both for men and for women. Compared with low level group, high level of effort, overcommitment, and ERI significantly increased risk of elevated fibrinogen (more than mean concentration) with adjusted OR of 3.3, 12.5, and 7.7 for men; 2.9, 7.2, and 7.2 for women, respectively; however, high reward reduced 80% risk for elevated fibrinogen.

Conclusions Effort, overcommitment, and ERI are significantly associated with fibrinogen among Chinese workers. High fibrinogen may be a possible link between job stress and cardiovascular disease. Am. J. Ind. Med. 55: 167-175, 2012. (C) 2011 Wiley Periodicals, Inc.

语种: 英语
所属项目编号: 2007CB512107
项目资助者: Major National Basic Research Program of the PR China
WOS记录号: WOS:000298734000008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58748
Appears in Collections:北京大学第三临床医学院_心血管内科_期刊论文

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作者单位: 1.Peking Univ Shenzhen Hosp, Dept Geriatr, Shenzhen, Peoples R China
2.Minist Educ, Key Lab Mol Cardiovasc Sci, Beijing, Peoples R China
3.Peking Univ Third Hosp, Dept Cardiol, Beijing 100191, Peoples R China
4.Peking Univ Third Hosp, Res Ctr Occupat Med, Beijing 100191, Peoples R China

Recommended Citation:
Xu, Weixian,Hang, Juan,Guo, Lijun,et al. Plasma fibrinogen: A possible link between job stress and cardiovascular disease among Chinese workers[J]. AMERICAN JOURNAL OF INDUSTRIAL MEDICINE,2012,55(2):167-175.
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