北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学临床肿瘤学院  > 期刊论文
学科主题: 临床医学
题名:
Preoperative chemotherapy with a trastuzumab-containing regimen for a patient with gastric cancer and hepatic metastases
作者: Li, Z. -Y.; Shan, F.; Zhang, L. -H.; Bu, Z. -D.; Wu, A. -W.; Wu, X. -J.; Zong, X. -L.; Li, S. -X.; Ji, X.; Ji, J. -F.
关键词: Trastuzumab ; Gastric adenocarcinoma ; HER2 ; Liver metastasis ; Distal gastrectomy
刊名: GENETICS AND MOLECULAR RESEARCH
发表日期: 2014
DOI: 10.4238/2014.December.19.17
卷: 13, 期:4, 页:10952-10957
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemistry & Molecular Biology ; Genetics & Heredity
研究领域[WOS]: Biochemistry & Molecular Biology ; Genetics & Heredity
关键词[WOS]: LIVER METASTASIS ; OXALIPLATIN ; RESECTION ; S-1
英文摘要:

Gastric cancer is the fourth most common cancer worldwide and the leading cause of tumor-related death in China. Gastric cancer is a heterogeneous disease and therefore requires different treatments based on the subtype. We describe a patient who had gastric cancer with liver metastases. Biopsy and tumor analysis using the HercepTest revealed a human epidermal growth factor receptor 2 (HER2)-positive adenocarcinoma as confirmed by fluorescence in situ hybridization. The patient was treated with a regimen of trastuzumab, oxaliplatin, and S-1 (six cycles). When positron emission tomography findings suggested that the metastases had resolved, the patient underwent surgery. Histopathologically, no cancer cells were observed in the resected hepatic tissue. The patient underwent tumor resection surgery, during which the tumor and gastric lymph nodes with lesions were removed. The patient has remained disease-free for 3 months. Therefore, trastuzumab may be an effective agent in the chemotherapeutic treatment of liver metastases in patients with HER2-positive gastric adenocarcinoma.

语种: 英语
所属项目编号: Z101107050210027
项目资助者: Major Cultivation Project of Beijing Medical Products and Technology
WOS记录号: WOS:000350229200132
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58755
Appears in Collections:北京大学临床肿瘤学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Sch Oncol, Dept Surg, Key Lab Carcinogenesis & Translat Res,Minist Educ, Beijing 100871, Peoples R China

Recommended Citation:
Li, Z. -Y.,Shan, F.,Zhang, L. -H.,et al. Preoperative chemotherapy with a trastuzumab-containing regimen for a patient with gastric cancer and hepatic metastases[J]. GENETICS AND MOLECULAR RESEARCH,2014,13(4):10952-10957.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Li, Z. -Y.]'s Articles
[Shan, F.]'s Articles
[Zhang, L. -H.]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Li, Z. -Y.]‘s Articles
[Shan, F.]‘s Articles
[Zhang, L. -H.]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace