北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学公共卫生学院  > 期刊论文
学科主题: 公共卫生
题名:
Levels of serum transferrin receptor and its response to Fe-supplement in Fe-deficient children
作者: Lin, Xiao-Ming; Ji, Cheng-Ye; Liu, Wen-Jing; Long, Zhu; Shen, Xiao-Yi
关键词: Fe deficiency ; children ; serum transferrin receptor ; Fe supplementation
刊名: BRITISH JOURNAL OF NUTRITION
发表日期: 2006-12-01
DOI: 10.1017/BJN20061954
卷: 96, 期:6, 页:1134-1139
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Nutrition & Dietetics
研究领域[WOS]: Nutrition & Dietetics
关键词[WOS]: IRON-DEFICIENCY ; DIAGNOSIS ; FERRITIN ; ADULTS ; INDEX ; TOOL
英文摘要:

The object of the present study was to investigate the levels of serum transferrin receptor (sTfR) and its response to Fe supplementation in Fe-deficient children and the role of sTfR in detecting Fe deficiency and assessing the efficacy of Fe supplementation. According to the diagnostic standard, 1006 children, aged 6-14 years in Fangshan district, Beijing, Peoples Republic of China, were divided into four groups: normal; Fe store depletion (IDs); Fe deficiency erythropoiesis (IDE); Fe deficiency anaemia (IDA). sTfR was determined and transferrin receptor-ferritin (TfR-F) index was calculated in 238 children, sixty-four normal and 174 Fe deficient. Children were administered a NaFeEDTA capsule containing 60 mg Fe once per week for the IDs and IDE groups and three times per week for the IDA group for nine consecutive weeks. The parameters reflecting Fe status and sTfR were determined before and after Fe supplementation. The levels of sTtR and TfR-F index in Fe-deficient children were significantly higher than those in the normal group. The receiver operating characteristic curve showed that sTfR has proper diagnostic efficacy for functional Fe deficiency. After Fe supplementation, the level of sTfR was significantly decreased in children with IDs, but not in children with IDE and IDA, while TfR-F index was significantly decreased in Fe-deficient children. sTfR is a reliable indicator for detecting functional Fe deficiency, and TfR-F index is a sensitive parameter for assessing the efficacy of Fe supplementation.

语种: 英语
WOS记录号: WOS:000244095600018
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58854
Appears in Collections:北京大学公共卫生学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Sch Publ Hlth, Dept Womens Child & Adolescent Hlth, Beijing 100083, Peoples R China
2.Peking Univ, Sch Publ Hlth, Dept Nutr & Food Hyg, Beijing 100083, Peoples R China

Recommended Citation:
Lin, Xiao-Ming,Ji, Cheng-Ye,Liu, Wen-Jing,et al. Levels of serum transferrin receptor and its response to Fe-supplement in Fe-deficient children[J]. BRITISH JOURNAL OF NUTRITION,2006,96(6):1134-1139.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Lin, Xiao-Ming]'s Articles
[Ji, Cheng-Ye]'s Articles
[Liu, Wen-Jing]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Lin, Xiao-Ming]‘s Articles
[Ji, Cheng-Ye]‘s Articles
[Liu, Wen-Jing]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace