IR@PKUHSC  > 北京大学第二临床医学院
学科主题临床医学
Prevalence and associated factors of obstructive sleep apnea in hospitalized patients with type 2 diabetes in Beijing, China
Zhang, Rui1; Guo, Xiaohui2; Guo, Lixin3; Lu, Juming4; Zhou, Xianghai1; Ji, Linong1
关键词cerebral infarction obstructive sleep apnea proliferative diabetic retinopathy type 2 diabetes
刊名JOURNAL OF DIABETES
2015
DOI10.1111/1753-0407.12180
7期:1页:16-23
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Endocrinology & Metabolism
研究领域[WOS]Endocrinology & Metabolism
关键词[WOS]HEART HEALTH ; MEN ; MECHANISMS ; DIAGNOSIS ; SCALE
英文摘要

BackgroundThe aim of the present study was to assess the prevalence and risk factors associated with obstructive sleep apnea (OSA) in hospitalized patients with type 2 diabetes mellitus (T2DM) in China.

MethodsPatients with T2DM who were hospitalized in four facilities in Beijing were invited to participate in the study. In all, 337 patients were enrolled consecutively, and 210 (62.3%) completed the study. Data from 472 patients in a non-consecutive expanding study were analyzed for the association study. A portable monitoring device was used to detect the presence of OSA. The apnea-hypopnea index (AHI) and the lowest level of oxygen saturation during the night were recorded to evaluate the severity of OSA. Logistic regression analysis was used to estimate the odds ratio (OR) for OSA for risk factors.

ResultsThe prevalence of OSA was 66.7%. The prevalence of moderate to severe OSA (AHI 15/h) was 20.0%. The multi-adjusted OR (95% confidence interval) estimating OSA corresponding to a 1-year increase in age was 1.06 (1.04, 1.08), whereas that to a 1-kg/m(2) increase in body mass index (BMI) was 1.18 (1.11, 1.26). The lowest oxygen saturation was associated with proliferative diabetic retinopathy (PDR) and cerebral infarction; the multivariate adjusted OR (95% CI) corresponding to a 1% increase in lowest oxygen saturation were 0.95 (0.92, 0.99) and 0.97 (0.94, 0.99), respectively.

ConclusionA high prevalence of OSA was observed in this sample of patients with T2DM in China. Age and BMI were associated with the presence of OSA. The lowest oxygen saturation was independently associated with the presence of PDR and cerebral infarction.

语种英语
WOS记录号WOS:000347041500005
项目编号2012AA02A509 ; D131100005313008
资助机构National High-Technology Research and Development of China (863 Program) ; Beijing Science and Technology Committee Funding
引用统计
被引频次:11[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/58898
专题北京大学第二临床医学院
北京大学第一临床医学院_内分泌内科
作者单位1.Beijing Hosp, Dept Endocrinol & Metab, Beijing, Peoples R China
2.Peking Univ, Peoples Hosp, Dept Endocrinol & Metab, Beijing 100044, Peoples R China
3.Peking Univ, Hosp 1, Dept Endocrinol & Metab, Beijing 100044, Peoples R China
4.Gen Hosp Peoples Liberat Army, Dept Endocrinol & Metab, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Rui,Guo, Xiaohui,Guo, Lixin,et al. Prevalence and associated factors of obstructive sleep apnea in hospitalized patients with type 2 diabetes in Beijing, China[J]. JOURNAL OF DIABETES,2015,7(1):16-23.
APA Zhang, Rui,Guo, Xiaohui,Guo, Lixin,Lu, Juming,Zhou, Xianghai,&Ji, Linong.(2015).Prevalence and associated factors of obstructive sleep apnea in hospitalized patients with type 2 diabetes in Beijing, China.JOURNAL OF DIABETES,7(1),16-23.
MLA Zhang, Rui,et al."Prevalence and associated factors of obstructive sleep apnea in hospitalized patients with type 2 diabetes in Beijing, China".JOURNAL OF DIABETES 7.1(2015):16-23.
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