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学科主题: 临床医学
题名:
Prevalence and associated factors of obstructive sleep apnea in hospitalized patients with type 2 diabetes in Beijing, China
作者: Zhang, Rui1; Guo, Xiaohui2; Guo, Lixin3; Lu, Juming4; Zhou, Xianghai1; Ji, Linong1
关键词: cerebral infarction ; obstructive sleep apnea ; proliferative diabetic retinopathy ; type 2 diabetes
刊名: JOURNAL OF DIABETES
发表日期: 2015
DOI: 10.1111/1753-0407.12180
卷: 7, 期:1, 页:16-23
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Endocrinology & Metabolism
研究领域[WOS]: Endocrinology & Metabolism
关键词[WOS]: HEART HEALTH ; MEN ; MECHANISMS ; DIAGNOSIS ; SCALE
英文摘要:

BackgroundThe aim of the present study was to assess the prevalence and risk factors associated with obstructive sleep apnea (OSA) in hospitalized patients with type 2 diabetes mellitus (T2DM) in China.

MethodsPatients with T2DM who were hospitalized in four facilities in Beijing were invited to participate in the study. In all, 337 patients were enrolled consecutively, and 210 (62.3%) completed the study. Data from 472 patients in a non-consecutive expanding study were analyzed for the association study. A portable monitoring device was used to detect the presence of OSA. The apnea-hypopnea index (AHI) and the lowest level of oxygen saturation during the night were recorded to evaluate the severity of OSA. Logistic regression analysis was used to estimate the odds ratio (OR) for OSA for risk factors.

ResultsThe prevalence of OSA was 66.7%. The prevalence of moderate to severe OSA (AHI 15/h) was 20.0%. The multi-adjusted OR (95% confidence interval) estimating OSA corresponding to a 1-year increase in age was 1.06 (1.04, 1.08), whereas that to a 1-kg/m(2) increase in body mass index (BMI) was 1.18 (1.11, 1.26). The lowest oxygen saturation was associated with proliferative diabetic retinopathy (PDR) and cerebral infarction; the multivariate adjusted OR (95% CI) corresponding to a 1% increase in lowest oxygen saturation were 0.95 (0.92, 0.99) and 0.97 (0.94, 0.99), respectively.

ConclusionA high prevalence of OSA was observed in this sample of patients with T2DM in China. Age and BMI were associated with the presence of OSA. The lowest oxygen saturation was independently associated with the presence of PDR and cerebral infarction.

语种: 英语
所属项目编号: 2012AA02A509 ; D131100005313008
项目资助者: National High-Technology Research and Development of China (863 Program) ; Beijing Science and Technology Committee Funding
WOS记录号: WOS:000347041500005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58898
Appears in Collections:北京大学第二临床医学院_期刊论文

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作者单位: 1.Beijing Hosp, Dept Endocrinol & Metab, Beijing, Peoples R China
2.Peking Univ, Peoples Hosp, Dept Endocrinol & Metab, Beijing 100044, Peoples R China
3.Peking Univ, Hosp 1, Dept Endocrinol & Metab, Beijing 100044, Peoples R China
4.Gen Hosp Peoples Liberat Army, Dept Endocrinol & Metab, Beijing, Peoples R China

Recommended Citation:
Zhang, Rui,Guo, Xiaohui,Guo, Lixin,et al. Prevalence and associated factors of obstructive sleep apnea in hospitalized patients with type 2 diabetes in Beijing, China[J]. JOURNAL OF DIABETES,2015,7(1):16-23.
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