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Achievement in SOD Mimics with Antioxidant and Anti-Inflammation Functions
Hu Ping1; Wu Gengwei1; Xia Qing2; Mao Zongwan1
关键词superoxide dismutase(SOD) SOD mimics antioxidant anti-inflammation
刊名PROGRESS IN CHEMISTRY
2009-05-01
21期:5页:873-879
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]SUPEROXIDE-DISMUTASE ACTIVITY ; IMIDAZOLATE-BRIDGED COPPER ; AIDED-DESIGN CAD ; ESCHERICHIA-COLI ; OXIDATIVE STRESS ; ACTIVE-SITE ; IN-VIVO ; DINUCLEAR COMPLEXES ; CATALYTIC-ACTIVITY ; CATALASE MIMETICS
英文摘要

As effective radical scavengers in vivo, superoxide dismutases (SODs) have the antioxidant, anti-inflammation and anti-aging functions, and have been applied in clinical treatments as drugs. Therefore, there is still an increasing interest in design and development of artificial SODs for potential application. In this article, a brief introduction about the research achievement of SOD mimics and their biomedical activities during past decade is shown. Our attention focuses on the relation between the structure and biological function of Cu, Zn-SOD mimics as well as the bio-activity and application of Mn-SOD mimics in medicine.

语种中文
WOS记录号WOS:000266016000009
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/58994
专题北京大学药学院
北京大学药学院_化学生物学系
作者单位1.Sun Yat Sen Univ, Sch Chem & Chem Engn, State Key Lab Biol Control, MOE Key Lab Bioinorgan & Synthet Chem, Guangzhou 510275, Guangdong, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
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GB/T 7714
Hu Ping,Wu Gengwei,Xia Qing,et al. Achievement in SOD Mimics with Antioxidant and Anti-Inflammation Functions[J]. PROGRESS IN CHEMISTRY,2009,21(5):873-879.
APA Hu Ping,Wu Gengwei,Xia Qing,&Mao Zongwan.(2009).Achievement in SOD Mimics with Antioxidant and Anti-Inflammation Functions.PROGRESS IN CHEMISTRY,21(5),873-879.
MLA Hu Ping,et al."Achievement in SOD Mimics with Antioxidant and Anti-Inflammation Functions".PROGRESS IN CHEMISTRY 21.5(2009):873-879.
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