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学科主题: 药学
题名:
Achievement in SOD Mimics with Antioxidant and Anti-Inflammation Functions
作者: Hu Ping1; Wu Gengwei1; Xia Qing2; Mao Zongwan1
关键词: superoxide dismutase(SOD) ; SOD mimics ; antioxidant ; anti-inflammation
刊名: PROGRESS IN CHEMISTRY
发表日期: 2009-05-01
卷: 21, 期:5, 页:873-879
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
关键词[WOS]: SUPEROXIDE-DISMUTASE ACTIVITY ; IMIDAZOLATE-BRIDGED COPPER ; AIDED-DESIGN CAD ; ESCHERICHIA-COLI ; OXIDATIVE STRESS ; ACTIVE-SITE ; IN-VIVO ; DINUCLEAR COMPLEXES ; CATALYTIC-ACTIVITY ; CATALASE MIMETICS
英文摘要:

As effective radical scavengers in vivo, superoxide dismutases (SODs) have the antioxidant, anti-inflammation and anti-aging functions, and have been applied in clinical treatments as drugs. Therefore, there is still an increasing interest in design and development of artificial SODs for potential application. In this article, a brief introduction about the research achievement of SOD mimics and their biomedical activities during past decade is shown. Our attention focuses on the relation between the structure and biological function of Cu, Zn-SOD mimics as well as the bio-activity and application of Mn-SOD mimics in medicine.

语种: 中文
WOS记录号: WOS:000266016000009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/58994
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Sun Yat Sen Univ, Sch Chem & Chem Engn, State Key Lab Biol Control, MOE Key Lab Bioinorgan & Synthet Chem, Guangzhou 510275, Guangdong, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Beijing 100191, Peoples R China

Recommended Citation:
Hu Ping,Wu Gengwei,Xia Qing,et al. Achievement in SOD Mimics with Antioxidant and Anti-Inflammation Functions[J]. PROGRESS IN CHEMISTRY,2009,21(5):873-879.
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