北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第二临床医学院  > 胸外科  > 期刊论文
学科主题: 临床医学
题名:
Application of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of mediastinal lesions
作者: Zhao Hui; Wang Jun; Zhou Zu-li; Li Yun; Bu Liang; Yang Fan; Sui Xi-zhao; Chen Ke-zhong; Li Xiao; Liu Jun; Li Jian-feng; Jiang Guan-chao
关键词: endobronchial ultrasound ; transbronchial needle aspiration ; mediastinal lesion ; diagnosis
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2011-12-05
DOI: 10.3760/cma.j.issn.0366-6999.2011.23.026
卷: 124, 期:23, 页:3988-3992
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: LUNG-CANCER ; RANDOMIZED-TRIAL ; LYMPH-NODES ; LYMPHADENOPATHY ; BIOPSY ; SARCOIDOSIS ; UTILITY ; MASSES
英文摘要:

Background Mediastinal lesions are often difficult to diagnose in clinical practice because of the unique anatomical position of the mediastinum, which makes performance of biopsy difficult. The value of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of lung cancer and mediastinal lymph node staging has been widely accepted. However, few studies have been conducted on the value of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis and differential diagnosis of mediastinal lesions. The current study was conducted to investigate the value of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis and differential diagnosis of isolated mediastinal lesions without lung abnormalities.

Methods We retrospectively analyzed the data of patients with isolated mediastinal lesions without lung abnormalities for whom endobronchial ultrasound-guided transbronchial needle aspiration examination was performed at the Department of Thoracic Surgery of Peking University People′s Hospital, between September 2009 and December 2010. For patients who could not be diagnosed with endobronchial ultrasound-guided transbronchial needle aspiration, surgical biopsy or more than 6 months of clinical and imaging follow-up was carried out.

Results Endobronchial ultrasound-guided transbronchial needle aspiration was performed for 60 patients with isolated mediastinal lesions. Correct diagnosis was made in 48 cases. Nineteen cases were malignant, and 29 were benign. The rate of correct diagnosis was 80%. The sensitivity, specificity, and accuracy of endobronchial ultrasound-guided transbronchial needle aspiration in distinguishing benign from malignant mediastinal lesions were 95%, 100%, and 98%, respectively. The examination was tolerable for all patients. No associated complications were observed.

Conclusion Endobronchial ultrasound-guided transbronchial needle aspiration is a safe and effective method of diagnosing mediastinal lesions. Chin Med J 2011;124(23):3988-3992

语种: 英语
WOS记录号: WOS:000299061300026
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59007
Appears in Collections:北京大学第二临床医学院_胸外科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Peoples Hosp, Dept Thorac Surg, Beijing 100044, Peoples R China

Recommended Citation:
Zhao Hui,Wang Jun,Zhou Zu-li,et al. Application of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of mediastinal lesions[J]. CHINESE MEDICAL JOURNAL,2011,124(23):3988-3992.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhao Hui]'s Articles
[Wang Jun]'s Articles
[Zhou Zu-li]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhao Hui]‘s Articles
[Wang Jun]‘s Articles
[Zhou Zu-li]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace