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Application of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of mediastinal lesions
Zhao Hui; Wang Jun; Zhou Zu-li; Li Yun; Bu Liang; Yang Fan; Sui Xi-zhao; Chen Ke-zhong; Li Xiao; Liu Jun; Li Jian-feng; Jiang Guan-chao
关键词endobronchial ultrasound transbronchial needle aspiration mediastinal lesion diagnosis
刊名CHINESE MEDICAL JOURNAL
2011-12-05
DOI10.3760/cma.j.issn.0366-6999.2011.23.026
124期:23页:3988-3992
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
研究领域[WOS]General & Internal Medicine
关键词[WOS]LUNG-CANCER ; RANDOMIZED-TRIAL ; LYMPH-NODES ; LYMPHADENOPATHY ; BIOPSY ; SARCOIDOSIS ; UTILITY ; MASSES
英文摘要

Background Mediastinal lesions are often difficult to diagnose in clinical practice because of the unique anatomical position of the mediastinum, which makes performance of biopsy difficult. The value of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of lung cancer and mediastinal lymph node staging has been widely accepted. However, few studies have been conducted on the value of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis and differential diagnosis of mediastinal lesions. The current study was conducted to investigate the value of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis and differential diagnosis of isolated mediastinal lesions without lung abnormalities.

Methods We retrospectively analyzed the data of patients with isolated mediastinal lesions without lung abnormalities for whom endobronchial ultrasound-guided transbronchial needle aspiration examination was performed at the Department of Thoracic Surgery of Peking University People′s Hospital, between September 2009 and December 2010. For patients who could not be diagnosed with endobronchial ultrasound-guided transbronchial needle aspiration, surgical biopsy or more than 6 months of clinical and imaging follow-up was carried out.

Results Endobronchial ultrasound-guided transbronchial needle aspiration was performed for 60 patients with isolated mediastinal lesions. Correct diagnosis was made in 48 cases. Nineteen cases were malignant, and 29 were benign. The rate of correct diagnosis was 80%. The sensitivity, specificity, and accuracy of endobronchial ultrasound-guided transbronchial needle aspiration in distinguishing benign from malignant mediastinal lesions were 95%, 100%, and 98%, respectively. The examination was tolerable for all patients. No associated complications were observed.

Conclusion Endobronchial ultrasound-guided transbronchial needle aspiration is a safe and effective method of diagnosing mediastinal lesions. Chin Med J 2011;124(23):3988-3992

语种英语
WOS记录号WOS:000299061300026
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59007
专题北京大学第二临床医学院_胸外科
北京大学基础医学院
北京大学第一临床医学院_眼科
作者单位Peking Univ, Peoples Hosp, Dept Thorac Surg, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Zhao Hui,Wang Jun,Zhou Zu-li,et al. Application of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of mediastinal lesions[J]. CHINESE MEDICAL JOURNAL,2011,124(23):3988-3992.
APA Zhao Hui.,Wang Jun.,Zhou Zu-li.,Li Yun.,Bu Liang.,...&Jiang Guan-chao.(2011).Application of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of mediastinal lesions.CHINESE MEDICAL JOURNAL,124(23),3988-3992.
MLA Zhao Hui,et al."Application of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of mediastinal lesions".CHINESE MEDICAL JOURNAL 124.23(2011):3988-3992.
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