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学科主题: 临床医学
题名:
Assessment of the minimum clinically important difference in neurological function and quality of life after surgery in cervical spondylotic myelopathy patients: a prospective cohort study
作者: Zhou, Feifei; Zhang, Yilong; Sun, Yu; Zhang, Fengshan; Pan, Shengfa; Liu, Zhongjun
关键词: Cervical spondylotic myelopathy ; Cervical spine ; Minimum clinically important difference ; Modified Japanese Orthopaedic Association score ; Short Form 36
刊名: EUROPEAN SPINE JOURNAL
发表日期: 2015-12-01
DOI: 10.1007/s00586-015-4208-3
卷: 24, 期:12, 页:2918-2923
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Orthopedics
研究领域[WOS]: Neurosciences & Neurology ; Orthopedics
关键词[WOS]: LOW-BACK-PAIN ; SHORT-FORM 36 ; MEDICAL OUTCOMES ; DISEASE ; QUESTIONNAIRE ; DISABILITY ; MANAGEMENT ; ARTICLE ; SF-36
英文摘要:

The purpose of this study was to evaluate the application of the minimum clinically important difference (MCID) concept to postoperative clinical results by using a prospective cohort study in Chinese patients with cervical spondylotic myelopathy (CSM).

The sample consisted of 113 patients who underwent surgical treatment for CSM in our hospital between February 2008 and November 2012. The preoperative and 1-year postoperative modified Japanese Orthopaedic Association (mJOA) scores, mJOA score recovery rate, physical component summary (PCS) and mental component summary (MCS) of the Short Form 36 were collected. The MCID of each outcome measurement was calculated by four approaches including average change, minimum detectable change, change difference and receiver operating characteristic curve. The responsiveness of each measurement was then analyzed.

The patients presented a statistically significant improvement (p < 0.01) postoperatively in mJOA, PCS, and MCS. The MCID calculated by four approaches varied from 4.09 to 9.62 for the PCS, 3.11 to 7.41 for the MCS, 1.25 to 3.07 for mJOA score, and 31.37 to 44.02 % for mJOA recovery rate. In addition, the improvement of the mJOA score owned the highest responsiveness of the four outcome measurements.

The threshold value of the MCID was determined by the choice of the assessment approach. In addition, the recovery rate of the mJOA score appeared to be the most valid and responsive measure of effectiveness of surgery in CSM patients.

语种: 英语
WOS记录号: WOS:000365875800029
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59033
Appears in Collections:北京大学第三临床医学院_骨科_期刊论文

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作者单位: Peking Univ, Dept Orthoped, Hosp 3, Beijing 100191, Peoples R China

Recommended Citation:
Zhou, Feifei,Zhang, Yilong,Sun, Yu,et al. Assessment of the minimum clinically important difference in neurological function and quality of life after surgery in cervical spondylotic myelopathy patients: a prospective cohort study[J]. EUROPEAN SPINE JOURNAL,2015,24(12):2918-2923.
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