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学科主题: 临床医学
题名:
Prognostic markers for idiopathic pulmonary arterial hypertension
作者: Guo Xiaomin; Jin Hongfang; Du Junbao
关键词: pulmonary arterial hypertension ; prognosis ; prognostic markers
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2014-11-05
DOI: 10.3760/cma.j.issn.0366-6999.20133265
卷: 127, 期:21, 页:3798-3802
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: LONG-TERM RESPONSE ; POOR-PROGNOSIS ; PLASMA-LEVELS ; SURVIVAL ; SEVERITY ; THERAPY ; FAILURE ; DIAGNOSIS ; EQUATION ; DISEASE
英文摘要:

Objective The objective of this study is to review the research on the prognostic markers of idiopathic pulmonary arterial hypertension (IPAH).

Date sources We searched literature from PubMed and CNKI databases both in English and Chinese up to 2013.

Study selection Data about mortality and cut-off value are from clinical trials and identified by analysis.

Results IPAH is an unexplained, progressive, and rare disease characterized by increased pulmonary artery pressure and pulmonary vascular resistance. The diagnosis is difficult, mortality of IPAH is high, and the survival periods are only 2-3 years after diagnosis. Investigations in recent years have identified a range of prognostic markers for IPAH, including the 6-minute walking test, red blood cell distribution width, and platelet levels, as well as imaging findings. Changes in these markers are important sources of information to predict the prognosis of patients with IPAH, which carries significant benefits for treatment planning.

Conclusion Even though the prognosis of IPAH has been investigated, the mortality is also high. More accurate and meaningful assessment for the prognosis of IPAH is required.

语种: 英语
所属项目编号: 7121014
项目资助者: Beijing Natural Science Foundation
WOS记录号: WOS:000346329300021
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59037
Appears in Collections:北京大学第一临床医学院_儿科_期刊论文

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作者单位: Peking Univ, Dept Pediat, Hosp 1, Beijing 100034, Peoples R China

Recommended Citation:
Guo Xiaomin,Jin Hongfang,Du Junbao. Prognostic markers for idiopathic pulmonary arterial hypertension[J]. CHINESE MEDICAL JOURNAL,2014,127(21):3798-3802.
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