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学科主题: 临床医学
题名:
ORAL HELICOBACTER PYLORI, ITS RELATIONSHIP TO SUCCESSFUL ERADICATION OF GASTRIC H. PYLORI AND SALIVA CULTURE CONFIRMATION
作者: Wang, X. M.1; Yee, K. C.2; Hazeki-Taylor, N.2; Li, J.1; Fu, H. Y.1; Huang, M. L.1; Zhang, G. Y.1
关键词: Helicobacter pylori ; rapid saliva diagnostic test ; urea breath test ; LGM mouthwash solution ; saliva H. pylori culture
刊名: JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
发表日期: 2014-08-01
卷: 65, 期:4, 页:559-566
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Physiology
研究领域[WOS]: Physiology
关键词[WOS]: DENTAL PLAQUE ; INFECTION ; STOMACH ; ESOPHAGUS ; THERAPY ; DISEASE ; CAVITY ; FECES
英文摘要:

The present study was designed to explore the existence of oral Helicobacter pylori (H. pylori), its relationship in the oral cavity to the success rate of eradication of the gastric H. pylori infection, and to determine if the mouthwash solution contained lysine (0.4%) and glycerol monolaurate (0.2%) (LGM) could eliminate oral H. pylori, as well as using the saliva H. pylori culture to confirm the existence of oral H. pylon. A total of 159 symptomatic individuals with stomach pain and 118 asymptomatic individuals with no stomach complaints, were recruited and tested using the saliva H. pylon antigen test (PPS), the H. pylori flagellin test (HPF), the urea breath test (UBT C-13) and the polymerase chain reaction (PCR) test, which tests were also confirmed by saliva culture. The test subjects also received various treatments. It was found that the H. pylori antigen exists in the oral cavity in UBT C-13 negative individuals. Traditional treatment for gastric eradication had only a 10.67 percent (10.67%) effectiveness rate on the oral H. pylori infection. In groups of patients with the oral H. pylori infection, but with negative UBT C-13, a mouthwash solution provided a 72.58% effectiveness rate in the 95% of the confidence interval (CI) ranges on the oral H. pylori infection. Traditional drug gastric eradication and teeth cleaning (TC) had less than a 10% effectiveness rate. Treatment of the oral infection increased the success rate of eradication of the stomach infection from 61.33% to 82.26% in the 95% CI ranges. We concluded that the successful rate of eradication of gastric H. pylon bears a significant relationship to the oral infection from H. pylori.

语种: 英语
WOS记录号: WOS:000343017300011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59109
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.Beijing Univ, Hosp 1, Beijing 100871, Peoples R China
2.Helicobacter Pylori Res Inst, Seattle, WA USA

Recommended Citation:
Wang, X. M.,Yee, K. C.,Hazeki-Taylor, N.,et al. ORAL HELICOBACTER PYLORI, ITS RELATIONSHIP TO SUCCESSFUL ERADICATION OF GASTRIC H. PYLORI AND SALIVA CULTURE CONFIRMATION[J]. JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY,2014,65(4):559-566.
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