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学科主题临床医学
ORAL HELICOBACTER PYLORI, ITS RELATIONSHIP TO SUCCESSFUL ERADICATION OF GASTRIC H. PYLORI AND SALIVA CULTURE CONFIRMATION
Wang, X. M.1; Yee, K. C.2; Hazeki-Taylor, N.2; Li, J.1; Fu, H. Y.1; Huang, M. L.1; Zhang, G. Y.1
关键词Helicobacter pylori rapid saliva diagnostic test urea breath test LGM mouthwash solution saliva H. pylori culture
刊名JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
2014-08-01
65期:4页:559-566
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Physiology
研究领域[WOS]Physiology
关键词[WOS]DENTAL PLAQUE ; INFECTION ; STOMACH ; ESOPHAGUS ; THERAPY ; DISEASE ; CAVITY ; FECES
英文摘要

The present study was designed to explore the existence of oral Helicobacter pylori (H. pylori), its relationship in the oral cavity to the success rate of eradication of the gastric H. pylori infection, and to determine if the mouthwash solution contained lysine (0.4%) and glycerol monolaurate (0.2%) (LGM) could eliminate oral H. pylori, as well as using the saliva H. pylori culture to confirm the existence of oral H. pylon. A total of 159 symptomatic individuals with stomach pain and 118 asymptomatic individuals with no stomach complaints, were recruited and tested using the saliva H. pylon antigen test (PPS), the H. pylori flagellin test (HPF), the urea breath test (UBT C-13) and the polymerase chain reaction (PCR) test, which tests were also confirmed by saliva culture. The test subjects also received various treatments. It was found that the H. pylori antigen exists in the oral cavity in UBT C-13 negative individuals. Traditional treatment for gastric eradication had only a 10.67 percent (10.67%) effectiveness rate on the oral H. pylori infection. In groups of patients with the oral H. pylori infection, but with negative UBT C-13, a mouthwash solution provided a 72.58% effectiveness rate in the 95% of the confidence interval (CI) ranges on the oral H. pylori infection. Traditional drug gastric eradication and teeth cleaning (TC) had less than a 10% effectiveness rate. Treatment of the oral infection increased the success rate of eradication of the stomach infection from 61.33% to 82.26% in the 95% CI ranges. We concluded that the successful rate of eradication of gastric H. pylon bears a significant relationship to the oral infection from H. pylori.

语种英语
WOS记录号WOS:000343017300011
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59109
专题北京大学第一临床医学院
北京大学第一临床医学院_消化科
作者单位1.Beijing Univ, Hosp 1, Beijing 100871, Peoples R China
2.Helicobacter Pylori Res Inst, Seattle, WA USA
推荐引用方式
GB/T 7714
Wang, X. M.,Yee, K. C.,Hazeki-Taylor, N.,et al. ORAL HELICOBACTER PYLORI, ITS RELATIONSHIP TO SUCCESSFUL ERADICATION OF GASTRIC H. PYLORI AND SALIVA CULTURE CONFIRMATION[J]. JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY,2014,65(4):559-566.
APA Wang, X. M..,Yee, K. C..,Hazeki-Taylor, N..,Li, J..,Fu, H. Y..,...&Zhang, G. Y..(2014).ORAL HELICOBACTER PYLORI, ITS RELATIONSHIP TO SUCCESSFUL ERADICATION OF GASTRIC H. PYLORI AND SALIVA CULTURE CONFIRMATION.JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY,65(4),559-566.
MLA Wang, X. M.,et al."ORAL HELICOBACTER PYLORI, ITS RELATIONSHIP TO SUCCESSFUL ERADICATION OF GASTRIC H. PYLORI AND SALIVA CULTURE CONFIRMATION".JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 65.4(2014):559-566.
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