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学科主题: 临床医学
题名:
Comparison of anterior ocular segment biometry features and related factors among American Caucasians, American Chinese and mainland Chinese
作者: Wang, Dandan1,2; Huang, Guofu1,2; He, Mingguang1; Wu, Lingling3; Lin, Shan2
关键词: anterior segment ; biometry ; Chinese ; optical coherence tomography
刊名: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
发表日期: 2012-08-01
DOI: 10.1111/j.1442-9071.2011.02746.x
卷: 40, 期:6, 页:542-549
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Ophthalmology
研究领域[WOS]: Ophthalmology
关键词[WOS]: PRIMARY ANGLE-CLOSURE ; CHAMBER DEPTH ; GLAUCOMA ; GREENLAND ; ESKIMOS
英文摘要:

Background: To compare the anterior segment biometric parameters amongst adult American Caucasians, American Chinese and mainland Chinese, in order to determine parameters that may contribute to increased risk for angle closure in Chinese.

Design: Cross-sectional clinic-based study

Participants: Four gender-and age-matched cohorts included Caucasians, American Chinese, Southern and Northern mainland Chinese.

Methods: Anterior segment optical coherence tomography was utilized to image the anterior chamber. Customized software was used to calculate the anterior segment parameters.

Main Outcome Measures: Anterior chamber depth, anterior chamber width, lens vault and corneal arc depth.

Results: Data from 121, 124, 121 and 120 subjects were available for American Caucasian, American Chinese, and Southern and Northern Mainland Chinese subjects, respectively. Caucasians had significantly greater anterior chamber depth, anterior chamber width and corneal arc depth than all Chinese groups even after adjustment for refractive status and axial length. In multiple regression analysis, predictors of greater lens vault were female gender, older age and more hyperopic/less myopic status for both racial groups. It was found only in Chinese that female and older subjects tended to have smaller anterior chamber depth, anterior chamber width and corneal arc depth.

Conclusion: The shallower anterior chamber in Chinese than Caucasians is likely attributable to the shorter corneal arc depth in the former group. Moreover, the smaller anterior chamber width contributes to more crowded anterior chambers in Chinese than in Caucasians. The more anteriorly located lens under a less vaulted cornea in Chinese females compared with Chinese males may account for the higher risk of angle closure in this subpopulation.

语种: 英语
所属项目编号: EY002161
项目资助者: George and Rosalie Hearst Foreign Fellowship ; That Man May See, Inc. ; Research to Prevent Blindness ; NEI
WOS记录号: WOS:000309604700004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59150
Appears in Collections:北京大学第三临床医学院_眼科_期刊论文

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作者单位: 1.Peking Univ, Ctr Eye, Hosp 3, Beijing 100871, Peoples R China
2.Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, Guangzhou 510275, Guangdong, Peoples R China
3.Univ Calif San Francisco, San Francisco, CA 94143 USA

Recommended Citation:
Wang, Dandan,Huang, Guofu,He, Mingguang,et al. Comparison of anterior ocular segment biometry features and related factors among American Caucasians, American Chinese and mainland Chinese[J]. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY,2012,40(6):542-549.
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